CAS 17685-04-0

Ethyl β-D-glucuronide

Description:

Ethyl β-D-glucuronide (EtG) is a metabolite of ethanol, formed through the conjugation of ethanol with glucuronic acid. It is a colorless, water-soluble compound that is often used as a biomarker for alcohol consumption due to its presence in urine and other biological fluids after ethanol intake. EtG is characterized by its stability, which allows it to be detected for a longer period compared to ethanol itself, making it a useful tool in alcohol testing. The compound is non-volatile and has a relatively low molecular weight. Its synthesis involves the enzymatic action of UDP-glucuronosyltransferases, which facilitate the transfer of glucuronic acid to various substrates, including ethanol. Ethyl β-D-glucuronide is also of interest in pharmacology and toxicology, as it can provide insights into alcohol metabolism and its effects on the body. Due to its specific formation from ethanol, it serves as a reliable indicator of recent alcohol consumption, aiding in both clinical and forensic investigations.

Formula: C₈H₁₄O₇

InChI: InChI=1S/C8H14O7/c1-2-14-8-5(11)3(9)4(10)6(15-8)7(12)13/h3-6,8-11H,2H2,1H3,(H,12,13)/t3-,4-,5+,6-,8+/m0/s1

InChI key: InChIKey=IWJBVMJWSPZNJH-UQGZVRACSA-N

SMILES: C(O)(=O)[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OCC)O1

Synonyms:

• 6-Ethoxy-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylicAcid
• Ba 2829
• Ethyl -D-glucuronide
• Ethyl Glucuronide
• Ethyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• Ethyl β-<span class="text-smallcaps">D</span>-glucosiduronic acid
• Ethyl β-<span class="text-smallcaps">D</span>-glucuronide
• Glucopyranosiduronic acid, ethyl, β-<span class="text-smallcaps">D</span>-
• ethyl D-glucopyranosiduronic acid
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, ethyl
• Ethyl β-D-Glucuronide
• β-D-Glucopyranosiduronic acid, ethyl
• Ethyl β-D-glucopyranosiduronic acid
• Ethyl β-D-glucosiduronic acid

Ethyl-β-D-glucuronide, 1mg/ml in Methanol

CAS: 17685-04-0

Color and Shape: Single Solution

Ref: LP-EGL-332-1LM

Ethyl-β-D-glucuronide

CAS: 17685-04-0

Color and Shape: Neat

Ref: LP-EGL-332-10

β-D-Glucopyranosiduronic acid, ethyl

CAS: 17685-04-0

Formula: C₈H₁₄O₇

Purity: 95%

Color and Shape: Solid

Molecular weight: 222.1926

Ref: IN-DA0024Z7

Ethyl b-D-glucuronide, 1mg/ml solution in Methanol

CAS: 17685-04-0

Formula: C₈H₁₄O₇

Molecular weight: 222.19

Ref: 7W-GW8904

Ethyl glucuronide

CAS: 17685-04-0

Ethyl glucuronide

Purity: ≥98%

Molecular weight: 222.19g/mol

Ref: 54-BUP01629

Ethyl b-D-glucuronide

CAS: 17685-04-0

Formula: C₈H₁₄O₇

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 222.19

Ref: 7W-GC5234

Ethyl glucuronide

CAS: 17685-04-0

Ethyl glucuronide (Ethyl-β-D-glucuronide) is a non-oxidized ethanol metabolite that is a biomarker of chronic alcohol consumption.

Formula: C₈H₁₄O₇

Purity: 99.56%

Color and Shape: Off-White Solid

Molecular weight: 222.19

Ref: TM-T11242

Ethyl D-Glucuronide

CAS: 17685-04-0

Formula: C₈H₁₄O₇

Molecular weight: 222.20

Ref: 4Z-A-862

Ethyl b-D-Glucuronide (1 mg/mL in Methanol)

Controlled Product

CAS: 17685-04-0

Formula: C₈H₁₄O₇

Color and Shape: Colourless

Molecular weight: 222.19

Ref: TR-KIT8320

Ethyl β-D-Glucuronide

CAS: 17685-04-0

Formula: C₈H₁₄O₇

Color and Shape: White To Beige

Molecular weight: 222.19

Ref: TR-E918425

Ethyl β-D-glucuronide

CAS: 17685-04-0

Ethyl β-D-glucuronide (EBG) is a metabolite of ethanol that is formed by the conjugation of glucuronic acid to ethanol in the liver. EBG has been shown to be a potential biomarker for alcohol consumption, as it can be detected in urine and blood. The presence of this molecule has also been associated with an increased risk of developing type 2 diabetes mellitus, cardiovascular disease, and cancer. EBG may also have pharmacological effects as it has been shown to inhibit lipid oxidation and increase insulin sensitivity. This molecule can be extracted from human serum using solid phase microextraction

Formula: C₈H₁₄O₇

Purity: Min. 98 Area-%

Color and Shape: Slightly Brown Powder

Molecular weight: 222.19 g/mol

Ref: 3D-ME07200

Ethyl glucuronide

CAS: 17685-04-0

Purity: 98%

Molecular weight: 222.07

Ref: 10-F557140

D3-Ethyl β-D-glucuronide

CAS: 17685-04-0

D3-Ethyl β-D-glucuronide is a metabolite of ethanol. Detection of this compound may be used to diagnose alcohol consumption during pregnancy. The detection time is approximately 5 hours after a single drink. D3-Ethyl β-D-glucuronide can be reliably detected in maternal blood using solid phase microextraction and LC-MS/MS methods. The body mass index (BMI) can be used to determine the risk for alcohol consumption during pregnancy, with higher BMIs indicating an increased risk. Logistic regression models were created to estimate the probability of D3-Ethyl β-D glucuronide being present in maternal blood and the probability of alcohol consumption during pregnancy given a positive result. These models were then used to create diagnostic tools that are sensitive enough for clinical use.

Formula: C₈H₁₁D₃O₇

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 225.21 g/mol

Ref: 3D-ME29306