CAS 1769-24-0

2-Methyl-4(3H)-quinazolinone

Description:

2-Methyl-4(3H)-quinazolinone, with the CAS number 1769-24-0, is an organic compound belonging to the quinazolinone class, characterized by a bicyclic structure that includes a quinazoline ring fused with a carbonyl group. This compound typically appears as a crystalline solid and is known for its pale yellow to off-white color. It exhibits moderate solubility in organic solvents such as ethanol and dimethyl sulfoxide, but is generally less soluble in water. The presence of the methyl group at the 2-position and the carbonyl at the 4-position contributes to its unique chemical reactivity and potential biological activity. 2-Methyl-4(3H)-quinazolinone has been studied for its pharmacological properties, including potential applications in medicinal chemistry, particularly as an intermediate in the synthesis of various bioactive compounds. Its stability under standard laboratory conditions makes it a useful compound for research and development in organic synthesis and drug discovery.

Formula: C₉H₈N₂O

InChI: InChI=1S/C9H8N2O/c1-6-10-8-5-3-2-4-7(8)9(12)11-6/h2-5H,1H3,(H,10,11,12)

InChI key: InChIKey=FIEYHAAMDAPVCH-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC(C)=N1)=CC=CC2

Synonyms:

• 2-Methyl-3,4-dihydroquinazolin-4-one
• 2-Methyl-3H-quinazolin-4-one
• 2-Methyl-4(3H)-quinazolone
• 2-Methyl-4-oxoquinazoline
• 2-Methyl-4-quinazolinol
• 2-Methyl-4-quinazolinone
• 2-Methyl-4-quinazolone
• 2-Methyl-chinazolinone(4)
• 2-Methyl-chinazolinone(4) [German]
• 2-Methylquinazolin-4(1H)-one
• 2-Methylquinazolone
• 3H-2-Methyl-4-oxoquinazoline
• 4(1H)-Quinazolinone, 2-methyl-
• 4(1H)-Quinazolinone, 2-methyl- (7CI,9CI)
• 4(3H)-Quinazolinone, 2-methyl-
• 4-Hydroxy-2-methylquinazoline
• 4-Quinazolinol, 2-methyl-
• 4-Quinazolinol, 2-methyl- (8CI)
• Ai3-52030
• Aurora Ka-3754
• B 101
• Nsc 12005
• Nsc 2757

2-Methyl-4(1H)-quinazolinone

CAS: 1769-24-0

Formula: C₉H₈N₂O

Purity: >98.0%(GC)(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 160.18

Ref: 3B-M2709

2-Methylquinazolin-4-ol

CAS: 1769-24-0

Formula: C₉H₈N₂O

Purity: 95%

Color and Shape: Solid

Molecular weight: 160.1726

Ref: IN-DA003HQG

2-Methylquinazolin-4-ol

CAS: 1769-24-0

2-Methylquinazolin-4-ol

Purity: ≥98%

Molecular weight: 160.17g/mol

Ref: 54-BUP17889

2-Methylquinazolin-4-ol

CAS: 1769-24-0

Compound 1769-24-0 is a natural product for research related to life sciences. The catalog number is TPL0186 and the CAS number is 1769-24-0.

Formula: C₉H₈N₂O

Purity: 99.98%

Color and Shape: Solid

Molecular weight: 160.17

Ref: TM-TPL0186

2-Methylquinazolin-4-Ol

CAS: 1769-24-0

2-Methylquinazolin-4-Ol

Purity: 98%

Molecular weight: 160.17g/mol

Ref: 54-OR1010564

2-Methylquinazolin-4-ol

CAS: 1769-24-0

Formula: C₉H₈N₂O

Purity: 97%

Color and Shape: Liquid, No data available.

Molecular weight: 160.176

Ref: 10-F319049

2-Methyl-4(3H)-quinazolinone

CAS: 1769-24-0

2-Methyl-4(3H)-quinazolinone is a quinazolinone that has been found to be an inhibitor of tumor necrosis factor-α (TNF-α) production. This compound also has strong antibacterial activity against Staphylococcus aureus and Bacillus subtilis. 2-Methyl-4(3H)-quinazolinone inhibits bacterial growth by binding to DNA dependent RNA polymerase, preventing transcription and replication. The high frequency of human activity has been shown using a patch clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 2-Methyl-4(3H)-quinazolinone also specifically binds to markers expressed at high levels in

Formula: C₉H₈N₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 160.17 g/mol

Ref: 3D-FM171915