CAS 17695-48-6

4-Methylumbelliferyl palmitate

Description:

4-Methylumbelliferyl palmitate is a synthetic compound commonly used as a substrate in biochemical assays, particularly for the detection of lipase and other enzymes. It is an ester formed from palmitic acid and 4-methylumbelliferone, a fluorescent compound. This substance is characterized by its ability to release 4-methylumbelliferone upon enzymatic hydrolysis, which can be quantitatively measured due to its fluorescent properties. The compound is typically a white to off-white solid and is soluble in organic solvents, while its solubility in water is limited. Its fluorescence can be excited at specific wavelengths, making it useful in various analytical applications, including enzyme activity assays and cellular imaging. Additionally, 4-Methylumbelliferyl palmitate is often employed in research settings to study lipid metabolism and enzyme kinetics. Safety data indicates that, like many chemical substances, it should be handled with care, following appropriate safety protocols to minimize exposure and environmental impact.

Formula: C₂₆H₃₈O₄

InChI: InChI=1S/C26H38O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-25(27)29-22-17-18-23-21(2)19-26(28)30-24(23)20-22/h17-20H,3-16H2,1-2H3

InChI key: InChIKey=QKQVFFACWLFRRX-UHFFFAOYSA-N

SMILES: CC=1C=2C(=CC(OC(CCCCCCCCCCCCCCC)=O)=CC2)OC(=O)C1

Synonyms:

• 4-Methylumbelliferone palmitate
• 4-Methylumbelliferyl palmitate
• 4-methyl-2-oxo-2H-chromen-7-yl hexadecanoate
• Coumarin, 7-hydroxy-4-methyl-, palmitate
• Hexadecanoic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
• Palmitic acid, ester with 7-hydroxy-4-methylcoumarin
• Palmitoyl 4-methylumbelliferone
• 4-Methyl-2-oxo-2H-1-benzopyran-7-yl palmitate

4-Methylumbelliferyl palmitate

CAS: 17695-48-6

Formula: C₂₆H₃₈O₄

Purity: ≥ 99.0%

Color and Shape: White powder

Molecular weight: 414.58

Ref: 7W-GK0388

4-Methylumbelliferyl palmitate

CAS: 17695-48-6

4-Methylumbelliferyl palmitate serves as a potent fluorophore to assay acid lipase activity in human leukocytes, with its fluorescence significantly affected by

Formula: C₂₆H₃₈O₄

Color and Shape: Solid

Molecular weight: 414.58

Ref: TM-T83314

4-Methylumbelliferyl palmitate

CAS: 17695-48-6

4-Methylumbelliferyl palmitate

Formula: C₂₆H₃₈O₄

Purity: 98%

Color and Shape: white powder

Molecular weight: 414.57752g/mol

Ref: 54-BIM1102

4-Methylumbelliferyl Palmitate

Controlled Product

CAS: 17695-48-6

Applications Fatty acyl esters of 4-methylumbelliferone for use as fluorogenic substrates to continuously follow the hydrolytic activity of carboxylesterases, such as acid and alkaline lipases.
References Jacks, T.J., et al.: Anal. Biochem., 21, 279 (1967), Baillargeon, M.W., et al.: Lipids, 26, 831 (1991),

Formula: C₂₆H₃₈O₄

Color and Shape: Neat

Molecular weight: 414.58

Ref: TR-M333070

4-Methylumbelliferyl palmitate

CAS: 17695-48-6

4-Methylumbelliferyl palmitate, commonly names as 4-MUP, is a fluorescent probe that binds to lipases, enzymes responsible to assist on the hydrolysis of fats. In diagnosis, 4-MUP is used for screening of lysosomal storage diseases (LSD) caused by a deficiency of a single enzyme involved in the metabolism of glycoproteins, lipids or mucopolysaccharides.

Formula: C₂₆H₃₈O₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 414.58 g/mol

Ref: 3D-EM35421

4-Methylumbelliferyl palmitate

CAS: 17695-48-6

Fluorogenic substrate for esterase yielding a blue fluorescent solution upon cleavage.

Formula: C₂₆H₃₈O₄

Purity: Min. 99 Area-%

Molecular weight: 414.59 g/mol

Ref: 3D-M-5750