Ac-Phe-Arg-AMC·HCl, also known as Acetyl-Phenylalanine-Arginine-AMC Hydrochloride, is a synthetic peptide substrate commonly used in biochemical research, particularly in studies involving proteases and enzyme activity. This compound features an acetyl group (Ac) attached to phenylalanine (Phe) and arginine (Arg), with 7-amino-4-methylcoumarin (AMC) serving as a fluorescent reporter group. The hydrochloride (HCl) form indicates that the compound is in a salt form, which enhances its solubility in aqueous solutions. Ac-Phe-Arg-AMC is characterized by its ability to release the fluorescent AMC upon cleavage by specific proteases, making it a valuable tool for monitoring enzyme activity in real-time. The fluorescence emitted can be quantitatively measured, allowing researchers to assess the kinetics of enzyme reactions. This compound is typically used in laboratory settings and is not intended for therapeutic use. Proper handling and storage conditions are essential to maintain its stability and efficacy in experimental applications.

Ac-Phe-Arg-AMC . HCl

177028-04-5: Ac-Phe-Arg-AMC·HCl, also known as Acetyl-Phenylalanine-Arginine-AMC Hydrochloride, is a synthetic peptide substrate commonly used in biochemical research, particularly in studies involving proteases and enzyme activity. This compound features an acetyl group (Ac) attached to phenylalanine (Phe) and arginine (Arg), with 7-amino-4-methylcoumarin (AMC) serving as a fluorescent reporter group. The hydrochloride (HCl) form indicates that the compound is in a salt form, which enhances its solubility in aqueous solutions. Ac-Phe-Arg-AMC is characterized by its ability to release the fluorescent AMC upon cleavage by specific proteases, making it a valuable tool for monitoring enzyme activity in real-time. The fluorescence emitted can be quantitatively measured, allowing researchers to assess the kinetics of enzyme reactions. This compound is typically used in laboratory settings and is not intended for therapeutic use. Proper handling and storage conditions are essential to maintain its stability and efficacy in experimental applications.

<p>Ac-Phe-Arg-AMC hydrochloride is a versatile building block that is used in the synthesis of complex compounds and research chemicals.<br>It is a fine chemical with CAS No. 177028-04-5. Ac-Phe-Arg-AMC hydrochloride is soluble in water, ethanol, and acetone, and insoluble in ether. This compound can be used as an intermediate for the synthesis of research chemicals with high quality or as a reagent. Ac-Phe-Arg-AMC hydrochloride can be used to produce a variety of useful scaffolds for medicinal chemistry or organic chemistry applications.</p>

CAS 177028-04-5

Ac-Phe-Arg-AMC . HCl

Ac-Phe-Arg-AMC hydrochloride

Ref: 3D-FA110473