CAS 1771-19-3

3-methoxy-10H-phenothiazine

Description:

3-Methoxy-10H-phenothiazine, with the CAS number 1771-19-3, is a chemical compound belonging to the phenothiazine class, which is characterized by a tricyclic structure containing sulfur and nitrogen atoms. This compound features a methoxy group (-OCH3) at the 3-position of the phenothiazine ring, which can influence its chemical reactivity and biological activity. Typically, phenothiazines are known for their use in pharmaceuticals, particularly as antipsychotic agents, due to their ability to interact with neurotransmitter systems in the brain. The presence of the methoxy group may enhance lipophilicity, potentially affecting the compound's solubility and permeability. In terms of physical properties, 3-methoxy-10H-phenothiazine is likely to be a solid at room temperature, with a specific melting point and boiling point that can vary based on purity and environmental conditions. Its chemical behavior can be influenced by factors such as pH and the presence of other reactive species, making it of interest in both synthetic and medicinal chemistry contexts.

Formula: C₁₃H₁₁NOS

InChI: InChI=1/C13H11NOS/c1-15-9-6-7-11-13(8-9)16-12-5-3-2-4-10(12)14-11/h2-8,14H,1H3

InChI key: InChIKey=NKRGJNZQQYCJHD-UHFFFAOYSA-N

SMILES: O(C)C=1C=C2C(NC=3C(S2)=CC=CC3)=CC1

Synonyms:

• 10H-Phenothiazine, 3-methoxy-
• 3-Methoxyphenothiazine
• Phenothiazine, 3-methoxy-
• 3-Methoxy-10H-phenothiazine

10H-Phenothiazine, 3-methoxy-

CAS: 1771-19-3

Formula: C₁₃H₁₁NOS

Molecular weight: 229.2975

Ref: IN-DA002542

3-Methoxy-10H-phenothiazine

Controlled Product

CAS: 1771-19-3

Applications 3-Methoxy-10H-phenothiazine is used in the synthesis of 10-Dechlorovancomycin (D226740), which is an impurity of Vancomycin (V096500, HCl salt) which is an amphoteric glycopeptide antibiotic produced by Streptomyces orientalis discovered in soil. Vancomycin inhibits bacterial cell wall synthesis by binding to peptidoglycan.
References Marshall, F.J., et al.: J. Med. Chem., 8, 18 (1965), Cunha, B.A., et al.: Med. Clin. North Am., 79, 817 (1995), Li, L., et al.: Ther. Drug Monit., 17, 366 (1995)

Formula: C₁₃H₁₁NOS

Color and Shape: Neat

Molecular weight: 229.3

Ref: TR-M265405

3-Methoxy phenothiazine

CAS: 1771-19-3

Formula: C₁₃H₁₁NOS

Molecular weight: 229.3

Ref: ST-EA-CP-L72013