CAS 1772-03-8

Galactosamine hydrochloride

Description:

Galactosamine hydrochloride is an amino sugar derivative of galactose, characterized by the presence of an amino group (-NH2) at the C-2 position. It is typically encountered as a white to off-white crystalline powder that is soluble in water, making it suitable for various biochemical applications. The hydrochloride form enhances its stability and solubility in aqueous solutions. Galactosamine plays a significant role in the biosynthesis of glycoproteins and glycolipids, contributing to cellular structure and function. It is also involved in metabolic pathways and has been studied for its potential therapeutic applications, particularly in the context of joint health and inflammation. The compound is generally handled with standard laboratory safety precautions, as it may cause irritation upon contact with skin or eyes. Its molecular formula reflects its composition of carbon, hydrogen, nitrogen, and chlorine, and it is important to consider its properties in the context of its reactivity and interactions with other biochemical substances.

Formula: C₆H₁₃NO₅·ClH

InChI: InChI=1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4+,5+,6-;/m0./s1

InChI key: InChIKey=CBOJBBMQJBVCMW-NQZVPSPJSA-N

SMILES: [C@H]([C@H]([C@@H](CO)O)O)([C@H](C=O)N)O.Cl

Synonyms:

• 2-Amino-2-Deoxyhexopyranose Hydrochloride
• 2-Amino-2-deoxy-<span class="text-smallcaps">D</span>-galactose hydrochloride
• 2-Amino-2-deoxy-D-galactopyranose hydrochloride
• 2-ammonio-2-deoxy-alpha-D-galactopyranose
• 2-ammonio-2-deoxy-beta-D-galactopyranose
• <span class="text-smallcaps">D</span>-Galactosamine hydrochloride
• <span class="text-smallcaps">D</span>-Galactose, 2-amino-2-deoxy-, hydrochloride
• <span class="text-smallcaps">D</span>-Galactose, 2-amino-2-deoxy-, hydrochloride (1:1)
• Chondrosamine hydrochloride
• D(+)Galactosamine, HCl
• D-Chondrosamine hydrochloride
• D-Glactosamine Hydrochloride
• Galactosamine hydrochloride
• Galactose, 2-amino-2-deoxy-, hydrochloride, <span class="text-smallcaps">D</span>-
• D(+)Galactosamine hydrochloride
• Galactose, 2-amino-2-deoxy-, hydrochloride, D-
• D-Galactosamine hydrochloride
• D(+)-Galactosamine hydrochloride
• D-Galactose, 2-amino-2-deoxy-, hydrochloride
• D(+)-Galactosamine Hydrochloride
• D-Galactose, 2-amino-2-deoxy-, hydrochloride (1:1)
• D-Galactosamine hydrochloride

D-(+)-Galactosamine Hydrochloride

CAS: 1772-03-8

Formula: C₆H₁₃NO₅·HCl

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 215.63

Ref: 3B-G0007

Galactosamine Hydrochloride

CAS: 1772-03-8

Heterocyclic compounds with oxygen hetero-atom(s) only, nesoi

Formula: C₆H₁₃NO₅·ClH

Color and Shape: Powder

Molecular weight: 215.05605

Ref: 45-1287722

D-Galactosamine, HCl

CAS: 1772-03-8

Formula: C₆H₁₄ClNO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 215.6321

Ref: IN-DA002566

D-(+)-Galactosamine hydrochloride

CAS: 1772-03-8

D-(+)-Galactosamine hydrochloride

Formula: C₆H₁₃NO₅·ClH

Purity: 98% (nmr) (Typical Value in Batch COA)

Color and Shape: white solid

Molecular weight: 215.63g/mol

Ref: 54-BIG5002

D(+)-Galactosamine hydrochloride

CAS: 1772-03-8

D(+)-Galactosamine hydrochloride

Purity: ≥95%

Molecular weight: 215.63g/mol

Ref: 54-BUP14595

D-(+)-Galactosamine hydrochloride

CAS: 1772-03-8

Formula: C₆H₁₃NO₅·HCl

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 215.64

Ref: 7W-GC4603

D(+)-Galactosamine hydrochloride

CAS: 1772-03-8

D(+)-Galactosamine hydrochloride (D-Galactosamine HCl) hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice.

Formula: C₆H₁₄ClNO₅

Purity: 99.855% - ≥95%

Color and Shape: White Powder

Molecular weight: 215.63

Ref: TM-T3999

D-Galactosamine, Hydrochloride

Controlled Product

CAS: 1772-03-8

Applications Specifically inhibits COX-2 by preventing COX-2 N-glycosylation and by increasing COX-2 protein turnover in a proteasome-dependent manner.
References Inoue, H., et al.: J. Biol. Chem., 270, 24965 (1995), Smith, W., et al.: Adv. Immunol., 62, 167 (1996), Nemeth, J., et al.: Biochemistry, 40, 3109 (2001), Tamura, M., et al.: J. Clin. Endocrinol. Metab., 87, 3263 (2002),

Formula: C₆H₁₃NO₅·ClH

Color and Shape: Neat

Molecular weight: 215.63

Ref: TR-G155000

D-Galactosamine hydrochloride

CAS: 1772-03-8

D-Galactosamine (GalN) is an aldohexose (2-Amino-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by an amino group (Collins, 2006). Galactosamine (as the N-Acetyl derivative) forms a key part of both N- and O-linked glycoproteins, glycolipids and glycosaminoglycans. Treatment of experimental animals with D-galactosamine / lipopolysaccharide causes lethal liver injury characterized by apoptosis of the hepatocyte and it is used as a laboratory model to study the effect of therapeutic agents (Hirono, 2001).

Formula: C₆H₁₄ClNO₅

Molecular weight: 215.63 g/mol

Ref: 3D-G-1500

D-Galactosamine hydrochloride

CAS: 1772-03-8

D-Galactosamine (GalN) is an aldohexose (2-amino-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by an amino group (Collins, 2006). Galactosamine (as the N-acetyl derivative) forms a key part of both N- and O-linked glycoproteins, glycolipids and glycosaminoglycans. Treatment of experimental animals with D-galactosamine / lipopolysaccharide causes lethal liver injury characterized by apoptosis of the hepatocyte and it is used as a laboratory model to study the effect of therapeutic agents (Hirono, 2001).

Formula: C₆H₁₃NO₅·HCl

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 215.63 g/mol

Ref: 3D-MG05030

D-Galactosamine hydrochloride - Synthetic origin

CAS: 1772-03-8

D-Galactosamine (GalN) is an aldohexose (2-Amino-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by an amino group (Collins, 2006). Galactosamine (as the N-Acetyl derivative) forms a key part of both N- and O-linked glycoproteins, glycolipids and glycosaminoglycans. Treatment of experimental animals with D-galactosamine / lipopolysaccharide causes lethal liver injury characterized by apoptosis of the hepatocyte and it is used as a laboratory model to study the effect of therapeutic agents (Hirono, 2001).

Formula: C₆H₁₃NO₅·HCl

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 215.63 g/mol

Ref: 3D-MG158512

D-Galactoseamine hydrochloride

CAS: 1772-03-8

Formula: C₆H₁₄ClNO₅

Purity: 97%

Color and Shape: Crystalline

Molecular weight: 215.63

Ref: 10-F093916

D-Galactosamine Hydrochloride extrapure, 98%

CAS: 1772-03-8

Formula: C₆H₁₄ClNO₅

Purity: min. 98%

Color and Shape: White to off white, Crystalline powder, Clear, Colourless to pale yellow

Molecular weight: 215.63

Ref: SR-14725