CAS 177325-13-2

Levofloxacin Hydrochloride

Description:

Levofloxacin Hydrochloride is a synthetic antibiotic belonging to the fluoroquinolone class, primarily used to treat a variety of bacterial infections. It is characterized by its broad-spectrum activity against both Gram-positive and Gram-negative bacteria, making it effective for respiratory tract infections, urinary tract infections, and skin infections. The compound is a chiral molecule, with its levorotatory form being the active isomer, which enhances its antibacterial efficacy compared to its racemic counterpart. Levofloxacin Hydrochloride is typically administered orally or intravenously and is known for its good bioavailability. Its mechanism of action involves inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription. The substance is generally well-tolerated, although it may cause side effects such as gastrointestinal disturbances, central nervous system effects, and, in rare cases, tendon damage. Due to its potential for developing resistance, it is important to use levofloxacin judiciously and in accordance with susceptibility patterns.

Formula: C₁₈H₂₀FN₃O₄·HCl

InChI: InChI=1/C18H20FN3O4.ClH/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21;/h7-8,10H,3-6,9H2,1-2H3,(H,24,25);1H/t10-;/m0./s1

InChI key: InChIKey=CAOOISJXWZMLBN-PPHPATTJSA-N

SMILES: O=C1C=2C3=C(C(=C(F)C2)N4CCN(C)CC4)OC[C@H](C)N3C=C1C(O)=O.Cl

Synonyms:

• (3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride
• (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride
• (S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride (1:1), (3S)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, monohydrochloride, (3S)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, monohydrochloride, (S)-
• Carboxylic Acid Monohydrochloride
• Levofloxacin Hcl
• LevofloxacinHydrochloride
• Weilisu
• Levofloxacin hydrochloride
• -7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride
• -9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)
• usp27 99% Levofloxacin white powder Antibacterial
• Levofloxacin white powder Antibacterial
• 3S)-9-Fluoro-2,3-dihydro-3-Methyl-10-(4-Methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid Monohydrochlori
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylicacid, 9-fluoro-2,3-dihydro-3-Methyl-10-(4-Methyl-1-piperazinyl)-7-oxo-,hydrochloride (1:1), (3S)-

7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride (1:1), (3S)-

CAS: 177325-13-2

Formula: C₁₈H₂₁ClFN₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 397.8284

Ref: IN-DA00258K

Levofloxacin hydrochloride

CAS: 177325-13-2

Formula: C₁₈H₂₀FN₃O₄·HCl

Purity: ≥ 89.0% (C18H20FN3O4, dried basis)

Color and Shape: Off-white to pale beige or light-yellow powder

Molecular weight: 397.9

Ref: 7W-GA2496

Levofloxacin Hydrochloride

CAS: 177325-13-2

Levofloxacin Hydrochloride

Purity: 99%

Molecular weight: 397.83g/mol

Ref: 54-PC109232

Levofloxacin hydrochloride

CAS: 177325-13-2

Levofloxacin hydrochloride

Purity: ≥98%

Molecular weight: 397.8g/mol

Ref: 54-BUP19621

Levofloxacin Hydrochloride

CAS: 177325-13-2

Formula: C₁₈H₂₀FN₃O₄·HCl

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 397.83

Ref: 3B-L0460

Levofloxacin hydrochloride

CAS: 177325-13-2

Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.

Formula: C₁₈H₂₁ClFN₃O₄

Purity: 99.78% - 99.98%

Color and Shape: Solid

Molecular weight: 397.8

Ref: TM-T8747

Levofloxacin hydrochloride

CAS: 177325-13-2

Levofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Levofloxacin has been shown to be effective against many infectious diseases, including urinary tract infections and some types of pneumonia. Levofloxacin also has inhibitory properties against gram-positive bacteria such as Streptococcus pyogenes and Staphylococcus aureus. The mechanism of action is not fully understood, but it is believed that levofloxacin interferes with protein synthesis by binding to the 30S subunit of the bacterial ribosome. The drug also binds to benzalkonium chloride (BAK) in wastewater treatment systems, which may contribute to its effectiveness in these

Formula: C₁₈H₂₀FN₃O₄•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 397.83 g/mol

Ref: 3D-FL104256

(S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride

CAS: 177325-13-2

Formula: C₁₈H₂₁ClFN₃O₄

Purity: 98%

Color and Shape: Solid, No data available.

Molecular weight: 397.83

Ref: 10-F054449

Levofloxacin Hydrochloride

CAS: 177325-13-2

Formula: C₁₈H₂₀FN₃O₄·(HCl)

Color and Shape: White To Light Beige

Molecular weight: 361.37 + (36.46)

Ref: TR-L360258