
CAS 1776112-90-3
:N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide
Description:
N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide is a complex organic compound characterized by its unique structural features, including a pyrrolidine ring, a purine derivative, and a methoxy-substituted pyrazole. The presence of a fluorine atom in the structure contributes to its potential biological activity, possibly influencing its interaction with biological targets. This compound is likely to exhibit specific pharmacological properties, making it of interest in medicinal chemistry and drug development. Its molecular structure suggests potential applications in areas such as cancer therapy or other diseases where purine metabolism plays a role. The acrylamide functional group may also indicate reactivity that could be exploited in further chemical modifications or conjugations. Overall, the compound's intricate design reflects a balance between structural complexity and potential therapeutic utility, warranting further investigation into its biological effects and mechanisms of action.
Formula:C18H22FN9O2
Synonyms:- 2-Propenamide, N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methyl-1H-pyrazol-4-yl)amino]-9-methyl-9H-purin-2-yl]-3-pyrrolidinyl]-
- Mavelertinib( PF-06747775)
- MAVELERTINIB
- N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methylpyrazol-4-yl)amino]-9-methylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide
- PF 6747775
- PF-06747775
- CPI-637
- N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide
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Found 3 products.
Mavelertinib
CAS:<p>Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.</p>Formula:C18H22FN9O2Purity:99.89%Color and Shape:SolidMolecular weight:415.42PF 06747775
CAS:<p>PF 06747775 is a growth factor that binds to the epidermal growth factor receptor (EGFR) and toll-like receptor 4 (TLR4), thereby inhibiting their downstream signaling. PF 06747775 has been shown to be effective in treating cancer, inflammatory diseases, and other diseases characterized by uncontrolled cell proliferation. It also inhibits the activity of CDK4/6, which regulates the G0/G1 phase transition in cells. PF 06747775 is administered systemically as a microsphere formulation for oral delivery. The drug is currently in Phase II clinical trials for its potential use as a treatment for cancer and inflammatory diseases.</p>Formula:C18H22FN9O2Purity:Min. 95%Molecular weight:415.4 g/mol



