CAS 177744-96-6

LY88074

CAS: 177744-96-6

LY88074

Purity: ≥98%

Molecular weight: 362.4g/mol

Ref: 54-BUP12846

Raloxifene Impurity 32

CAS: 177744-96-6

Formula: C₂₁H₁₄O₄S

Molecular weight: 362.41

Ref: 4Z-R-0150

LY 88074

Controlled Product

CAS: 177744-96-6

Impurity Raloxifene EP Impurity D
Applications LY 88074 is a selective estrogen receptor modulator (SERM). LY 88074 has potential use in the treatment of estrogen deprivation syndrome.
References Dai, S.Y. et al.: Proc. Nat. Acad. Sci. USA, 105, 7171 (2008); Dai, S.Y. et al.: Biochemistry, 48, 9668 (2009);

Formula: C₂₁H₁₄O₄S

Color and Shape: Neat

Molecular weight: 362.4

Ref: TR-L486900

[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl](4-hydroxyphenyl)-methanone

CAS: 177744-96-6

MDM2 inhibitors are a class of cancer drugs that inhibit the activity of MDM2, which is an oncoprotein that prevents the degradation of p53. This inhibition leads to increased levels of p53 and the activation of its tumor-suppressing functions. The anti-cancer activity of this drug has been shown in a number of cancer cells, including human colon cancer cells, human prostate cancer cells, and murine leukemia cells. Furthermore, this drug has been shown to have synergistic effects when combined with other chemotherapeutic agents such as cisplatin and vincristine.

Formula: C₂₁H₁₄O₄S

Purity: Min. 95%

Molecular weight: 362.4 g/mol

Ref: 3D-IH44805

Raloxifene Impurity 25

CAS: 177744-96-6

Formula: C₂₁H₁₄O₄S

Molecular weight: 362.4

Ref: ST-EA-CP-R2037

LY88074

CAS: 177744-96-6

LY88074, a raloxifene analog sans basic side chain, is an ERβ agonist (EC50 = 232 nM) that promotes uterine cell growth.

Formula: C₂₁H₁₄O₄S

Purity: 98.31%

Color and Shape: Solid

Molecular weight: 362.4

Ref: TM-T11915