CAS 17780-75-5: Clorgyline hydrochloride

Description: Clorgyline hydrochloride is a selective irreversible inhibitor of monoamine oxidase A (MAO-A), primarily used in research and clinical settings for its antidepressant properties. It is a white to off-white crystalline powder that is soluble in water and exhibits a moderate molecular weight. The compound acts by inhibiting the breakdown of neurotransmitters such as serotonin, norepinephrine, and dopamine, thereby increasing their availability in the synaptic cleft, which can enhance mood and alleviate symptoms of depression. Clorgyline hydrochloride has a specific affinity for MAO-A over MAO-B, making it a valuable tool in studying the role of monoamines in neurobiology. Its pharmacological profile includes potential side effects typical of MAO inhibitors, such as hypertensive crises when combined with tyramine-rich foods. Due to its irreversible nature, the effects of clorgyline can persist even after the drug is cleared from the system, necessitating careful monitoring during treatment. As with all medications, it is essential to use clorgyline hydrochloride under appropriate medical supervision.

Formula: C₁₃H₁₅Cl₂NO·ClH

InChI: InChI=1S/C13H15Cl2NO.ClH/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15;/h1,5-6,10H,4,7-9H2,2H3;1H

InChI key: InChIKey=BBAZDLONIUABKI-UHFFFAOYSA-N

SMILES: Cl.ClC1=CC=C(OCCCN(C)CC#C)C(Cl)=C1

Synonyms:

• 2-Propyn-1-amine, N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-, hydrochloride
• 2-Propyn-1-amine, N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-, hydrochloride (1:1)
• 2-Propynylamine, N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-, hydrochloride
• Clorgyline HCl
• Clorgyline hydrochloride
• M&B 9302
• N-(3-(2,4-Dichlorophenoxy)propyl)-N-methyl-2-propynylamine hydrochloride
• N-2,4-Dichlorophenoxypropyl-N-methylpropargylamine-HCl
• N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride
• N-[3-(2,4-dichlorophenoxy)propyl]-N-methylprop-2-yn-1-amine hydrochloride (1:1)
• Propylamine, 3-(2,4-dichlorophenoxy)-N-methyl-N-propargyl-, hydrochloride

Clorgyline hydrochloride

CAS: 17780-75-5

Clorgyline hydrochloride (Clorgiline hydrochloride), a white powder, is served as monoamine oxidase inhibitor.

• Formula: C₁₃H₁₅Cl₂NO·HCl
• Purity: 99.55% - 99.8%
• Color and Shape: Solid
• Molecular weight: 308.63

2-Propyn-1-amine, N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-, hydrochloride (1:1)

CAS: 17780-75-5

• Formula: C₁₃H₁₆Cl₃NO
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 308.6312

N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride

CAS: 17780-75-5

• Formula: C₁₃H₁₅Cl₂NO·HCl
• Molecular weight: 308.63

Clorgyline Hydrochloride

CAS: 17780-75-5

• Formula: C₁₃H₁₅Cl₂NO·ClH
• Color and Shape: Neat
• Molecular weight: 308.63

N-(3-(2,4-Dichlorophenoxy)propyl)-N-methylprop-2-yn-1-amine hydrochloride

CAS: 17780-75-5

• Purity: 95.0%
• Molecular weight: 308.6300048828125

Clorgyline Hydrochloride

CAS: 17780-75-5

Clorgyline hydrochloride is a monoamine neurotransmitter inhibitor that blocks the enzyme monoamine oxidase (MAO). It …

• Formula: C₁₃H₁₅Cl₂NO·HCl
• Purity: Min. 98 Area-%
• Color and Shape: White Off-White Powder
• Molecular weight: 308.63 g/mol