CAS 177905-10-1

methyl [4-(trifluoromethoxy)phenyl]carbamate

Description:

Methyl [4-(trifluoromethoxy)phenyl]carbamate is an organic compound characterized by its carbamate functional group, which is derived from the reaction of an amine with a carbonyl compound. This substance features a methyl ester linked to a phenyl ring that has a trifluoromethoxy substituent at the para position. The presence of the trifluoromethoxy group imparts unique electronic properties, enhancing the compound's lipophilicity and potentially influencing its biological activity. Methyl [4-(trifluoromethoxy)phenyl]carbamate is typically a solid at room temperature and is soluble in organic solvents. It may exhibit moderate to high stability under standard conditions, but like many carbamates, it can be sensitive to hydrolysis in the presence of strong acids or bases. This compound is of interest in various fields, including agrochemicals and pharmaceuticals, due to its potential applications as an insecticide or herbicide, as well as its role in medicinal chemistry. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance.

Formula: C₉H₈F₃NO₃

InChI: InChI=1S/C9H8F3NO3/c1-15-8(14)13-6-2-4-7(5-3-6)16-9(10,11)12/h2-5H,1H3,(H,13,14)

InChI key: InChIKey=RVSOYUOWAZHCFP-UHFFFAOYSA-N

SMILES: O(C(F)(F)F)C1=CC=C(NC(OC)=O)C=C1

Synonyms:

• Carbamic acid, [4-(trifluoromethoxy)phenyl]-, methyl ester
• In-Kb 687
• Methyl N-[4-(trifluoromethoxy)phenyl]carbamate
• [4-(Trifluoromethoxy)phenyl]carbamic Acid Methyl Ester
• carbamic acid, N-[4-(trifluoromethoxy)phenyl]-, methyl ester
• Methyl [4-(trifluoromethoxy)phenyl]carbamate

Indoxacarb metabolite IN-KB 687

CAS: 177905-10-1

Formula: C₉H₈F₃NO₃

Color and Shape: Neat

Molecular weight: 235.16

Ref: 04-C14325660

Indoxacarb Impurity 8

CAS: 177905-10-1

Formula: C₉H₈F₃NO₃

Molecular weight: 235.16

Ref: 4Z-I-066010

[4-(Trifluoromethoxy)phenyl]carbamic Acid Methyl Ester

Controlled Product

CAS: 177905-10-1

Applications [4-(Trifluoromethoxy)phenyl]carbamic Acid Methyl Ester is an intermediate in the synthesis of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.
References Luo, M., et al.: Asian. J. Chem., 24, 5148 (2012);

Formula: C₉H₈F₃NO₃

Color and Shape: Light Yellow

Molecular weight: 235.16

Ref: TR-T790750