CAS 177931-17-8

sauchinone

Description:

Sauchinone is a naturally occurring chemical compound classified as a sesquiterpene, primarily derived from the plant species *Saururus cernuus*, commonly known as lizard tail. It is characterized by its complex bicyclic structure, which contributes to its unique chemical properties. Sauchinone exhibits a range of biological activities, including anti-inflammatory, antioxidant, and potential anticancer effects, making it a subject of interest in pharmacological research. The compound is typically found in the form of a colorless to pale yellow liquid and has a distinctive odor. Its solubility varies, being more soluble in organic solvents than in water. The molecular formula of sauchinone reflects its composition of carbon, hydrogen, and oxygen atoms, which is typical for sesquiterpenes. Due to its bioactive properties, sauchinone is being explored for various therapeutic applications, although further studies are needed to fully understand its mechanisms of action and potential uses in medicine.

Formula: C₂₀H₂₀O₆

InChI: InChI=1/C20H20O6/c1-9-3-11-13(21)5-17-20(25-8-24-17)19(11)18(10(9)2)12-4-15-16(23-7-22-15)6-14(12)26-20/h4-6,9-11,18-19H,3,7-8H2,1-2H3/t9-,10+,11+,18+,19+,20+/m1/s1

InChI key: InChIKey=GMTJIWUFFXGFHH-WPAOEJHSSA-N

SMILES: C[C@@H]1[C@@]2([C@]3([C@]4(C(=CC(=O)[C@@]3(C[C@H]1C)[H])OCO4)OC=5C2=CC6=C(C5)OCO6)[H])[H]

Synonyms:

• (5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one
• (5aR,7R,8S,8aR,14aS,14bR)-7,8-dimethyl-5a,6,7,8,8a,14b-hexahydro-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one
• 5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-
• 5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aα,7α,8β,8aβ,14aS*,14bβ)-
• 5H-benzo[kl][1,3]dioxolo[4,5-b]-1,3-dioxolo[4,5-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-
• Sauchinone
• (5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one
• 5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-
• Sauchinone, 98%, from Saururus chinensis (Lour. ) Baill
• Sauchinone >=98% (HPLC)

Sauchinone

CAS: 177931-17-8

Formula: C₂₀H₂₀O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 356.3692

Ref: IN-DA00AP2Q

Sauchinone

CAS: 177931-17-8

Sauchinone

Purity: ≥98%

Molecular weight: 356.37g/mol

Ref: 54-BUP00983

Sauchinone

CAS: 177931-17-8

Sauchinone possesses diverse pharmacological properties, such as hepatoprotective, neuroprotective, anti-inflammatory and anti-tumor effects. Sauchinone protects skin keratinocytes through inhibition of extracellular signal-regulated kinase, c-Jun N-terminal kinase, and p38 MAPK signaling via upregulation of oxidative defense enzymes. Sauchinone can be used for the prevention of functional β-cell damage, it prevents cytokine-induced NO production, iNOS expression,JAK/STAT activation,and NF-κB activation and inhibition of glucose-stimulated insulin secretion (GSIS).

Formula: C₂₀H₂₀O₆

Purity: 95%~99%

Molecular weight: 356.374

Ref: BP-BP1258

Sauchinone

CAS: 177931-17-8

Sauchinone: Treats infections, prevents liver fibrosis, reduces oxidative stress, and protects skin and vascular cells.

Formula: C₂₀H₂₀O₆

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 356.37

Ref: TM-T6S1572

Sauchinone

CAS: 177931-17-8

Formula: C₂₀H₂₀O₆

Molecular weight: 356.4

Ref: 7W-GL5788

Sauchinone

CAS: 177931-17-8

Oxygen-heterocyclic compound

Formula: C₂₀H₂₀O₆

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 356.37

Ref: 5G-83906

Sauchinone

CAS: 177931-17-8

Sauchinone is a natural compound that has shown to be effective in the treatment of bowel disease. This compound is an inhibitor of the toll-like receptor (TLR) and has shown to reduce inflammation and oxidative injury. Sauchinone has been found to increase the production of growth factor-β1, which may be useful for treating injuries such as burns or wounds. The matrix effect of sauchinone on cell culture was investigated using dextran sulfate, which is known to induce apoptosis in cells. Chromatographic analysis showed that sauchinone inhibited DNA binding activity and had an effect on dna binding activity. Molecular docking analysis showed that sauchinone binds with TLR4 and inhibits its signaling pathway, preventing aberrant reactions from occurring. Sauchinone also inhibits NF-κB activation by inhibiting nuclear translocation, thus suppressing inflammatory response.

Formula: C₂₀H₂₀O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 356.37 g/mol

Ref: 3D-FS73944