CAS 177952-39-5

2,4-bis(trifluoromethyl)phenylacetic acid

Description:

2,4-Bis(trifluoromethyl)phenylacetic acid is an organic compound characterized by its unique structure, which includes a phenyl ring substituted with two trifluoromethyl groups and an acetic acid moiety. This compound is notable for its high lipophilicity and potential biological activity, making it of interest in pharmaceutical and agrochemical research. The presence of trifluoromethyl groups enhances the compound's metabolic stability and can influence its interaction with biological targets. It typically appears as a solid at room temperature and is soluble in organic solvents. The compound's acidity is attributed to the carboxylic acid functional group, which can participate in hydrogen bonding and influence its reactivity. Additionally, the trifluoromethyl groups can impart unique electronic properties, affecting the compound's overall reactivity and interaction with other molecules. Due to these characteristics, 2,4-bis(trifluoromethyl)phenylacetic acid may exhibit interesting pharmacological properties, although specific applications would depend on further research and development.

Formula: C₂₄H₂₀FNO₄

InChI: InChI=1/C24H20FNO4/c25-16-11-9-15(10-12-16)13-22(23(27)28)26-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14H2,(H,26,29)(H,27,28)

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=NC(Cc1ccc(cc1)F)C(=O)O)O

Synonyms:

• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-fluorophenylalanine
• 2,4-Ditrifluoromethylphenylacetic Acid

Benzeneacetic acid, 2,4-bis(trifluoromethyl)-

CAS: 177952-39-5

Formula: C₁₀H₆F₆O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 272.1439

Ref: IN-DA0025NK

2,4-Bis(trifluoromethyl)phenylacetic acid

CAS: 177952-39-5

2,4-Bis(trifluoromethyl)phenylacetic acid

Formula: C₁₀H₆F₆O₂

Purity: 98%

Color and Shape: white powder

Molecular weight: 272.14g/mol

Ref: 54-PC3202

2,4-Bis(trifluoromethyl)phenylacetic Acid

CAS: 177952-39-5

Formula: C₁₀H₆F₆O₂

Purity: >97.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 272.15

Ref: 3B-B5337

2,4-Bis(trifluoromethyl)phenylacetic acid

CAS: 177952-39-5

Formula: C₁₀H₆F₆O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 272.146

Ref: 10-F007830

2,4-Bis(trifluoromethyl)phenylacetic acid

CAS: 177952-39-5

2,4-Bis(trifluoromethyl)phenylacetic acid is an oxime that has been shown to be a regioselective and efficient alkylation agent for the synthesis of benzodiazepines. It can also be used as an antiarrhythmic drug. 2,4-Bis(trifluoromethyl)phenylacetic acid reacts with an aryl halide in the presence of a base to form the corresponding benzooxazinone. This reaction is catalytic and proceeds via oxidative cleavage with hydrogen peroxide or sodium perborate, followed by coupling with an appropriate amine to produce the desired benzodiazepine. The use of this reagent provides a simple and economical route to various benzodiazepinones that are not readily available from other routes of synthesis. This class of compounds is useful in treating anxiety disorders, insomnia, muscle spasms, seizures, and alcohol withdrawal

Formula: C₁₀H₆F₆O₂

Purity: Min. 95%

Molecular weight: 272.14 g/mol

Ref: 3D-FB63958