CAS 177966-58-4

3,4-Dichloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine

Description:

3,4-Dichloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine, with CAS number 177966-58-4, is a synthetic amino acid derivative characterized by the presence of a dichloro substituent and a fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound features a D-phenylalanine backbone, which is an enantiomer of phenylalanine, contributing to its unique stereochemical properties. The Fmoc group is commonly used in peptide synthesis as a protective group for the amino functionality, allowing for selective reactions without interfering with the amine. The dichloro substitution enhances the compound's hydrophobicity and may influence its biological activity, making it of interest in medicinal chemistry and peptide design. Additionally, the fluorenyl group provides stability and can facilitate purification processes. Overall, this compound is significant in the context of peptide synthesis and drug development, particularly in the design of bioactive peptides with enhanced properties.

Formula: C₂₄H₁₉Cl₂NO₄

InChI: InChI=1S/C24H19Cl2NO4/c25-20-10-9-14(11-21(20)26)12-22(23(28)29)27-24(30)31-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-11,19,22H,12-13H2,(H,27,30)(H,28,29)/t22-/m1/s1

InChI key: InChIKey=QNVHCYWPXIGFGN-JOCHJYFZSA-N

SMILES: C(OC(N[C@H](CC1=CC(Cl)=C(Cl)C=C1)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Synonyms:

• (2R)-3-(3,4-Dichlorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
• 3,4-Dichloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">D</span>-phenylalanine
• <span class="text-smallcaps">D</span>-Phenylalanine, 3,4-dichloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-D-3,4-Dichlorophe
• Fmoc-D-3,4-Dichlorophenylalanine
• 295: PN: US20070042401 PAGE: 38 claimed sequence
• D-Phenylalanine, 3,4-dichloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• 986: PN: WO2006135786 PAGE: 70 claimed sequence
• 3,4-Dichloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-phenylalanine

D-Phenylalanine, 3,4-dichloro-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 177966-58-4

Formula: C₂₄H₁₉Cl₂NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 456.3180

Ref: IN-DA0025OF

Fmoc-D-Phe(3,4-Cl2)-OH

CAS: 177966-58-4

Molecular weight: 456.32

Ref: 7W-GM9225

3,4-Dichloro-D-phenylalanine, N-FMOC protected

CAS: 177966-58-4

3,4-Dichloro-D-phenylalanine, N-FMOC protected

Formula: C₂₄H₁₉Cl₂NO₄

Purity: 95%

Color and Shape: pale yellow solid

Molecular weight: 456.32g/mol

Ref: 54-OR14609

FMOC-3,4-DICHLORO-D-PHENYLALANINE

CAS: 177966-58-4

Purity: 98%

Color and Shape: Solid

Molecular weight: 456.3200073

Ref: 10-F819240