CAS 17797-12-5

1-(4-Bromophenyl)-1-methylethylamine

Description:

1-(4-Bromophenyl)-1-methylethylamine, with the CAS number 17797-12-5, is an organic compound characterized by its amine functional group and a brominated phenyl substituent. This compound features a branched alkyl chain, specifically a 1-methylethyl group, attached to a nitrogen atom, which contributes to its basicity and potential reactivity. The presence of the bromine atom on the para position of the phenyl ring enhances its electrophilic character, making it a useful intermediate in various chemical syntheses. The compound is typically a colorless to pale yellow liquid or solid, depending on its purity and specific conditions. It is soluble in organic solvents, which facilitates its use in organic reactions. Due to the presence of the amine group, it can participate in hydrogen bonding, influencing its physical properties such as boiling point and solubility. Safety precautions should be taken when handling this compound, as it may pose health risks typical of amines and halogenated compounds.

Formula: C₉H₁₂BrN

InChI: InChI=1/C9H12BrN/c1-9(2,11)7-3-5-8(10)6-4-7/h3-6H,11H2,1-2H3

SMILES: CC(C)(c1ccc(cc1)Br)N

Synonyms:

• 1-(1-Amino-1-methylethyl)-4-bromobenzene
• 2-(4-Bromophenyl)Propan-2-Amine

Benzenemethanamine, 4-bromo-α,α-dimethyl-

CAS: 17797-12-5

Formula: C₉H₁₂BrN

Purity: 97%

Color and Shape: Liquid

Molecular weight: 214.1023

Ref: IN-DA0025ON

2-(4-Bromophenyl)propan-2-amine

CAS: 17797-12-5

2-(4-Bromophenyl)propan-2-amine

Purity: 98%

Color and Shape: Liquid

Molecular weight: 214.10g/mol

Ref: 54-OR900669

2-(4-Bromophenyl)propan-2-amine

CAS: 17797-12-5

Purity: 97%

Molecular weight: 214.11

Ref: 10-F601502

2-(4-Bromophenyl)propan-2-amine

CAS: 17797-12-5

2-(4-Bromophenyl)propan-2-amine (BPAP) is an analogue of the antihistamine diphenhydramine. The BPAP analogues are selective for protein kinases, such as vegfr-2, cyclin, and cdk1. VEGFR-2 is a receptor tyrosine kinase that is activated by vascular endothelial growth factor and plays a role in angiogenesis. Cyclin is a serine/threonine protein kinase that regulates the cell cycle and CDK1 regulates the progression from G1 to S phase. In vivo efficacy studies have shown that BPAP inhibits these three kinases with an IC50 value of less than 1 μM in human tumor cells.

Formula: C₉H₁₂BrN

Purity: Min. 95%

Molecular weight: 214.1 g/mol

Ref: 3D-SAA79712