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CAS 178119-93-2

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Fmoc-D-4-Hydroxyphenylglycine

Description:
Fmoc-D-4-Hydroxyphenylglycine is a derivative of phenylglycine, characterized by the presence of a 4-hydroxyphenyl group and a fluorenylmethyloxycarbonyl (Fmoc) protective group. This compound is commonly used in peptide synthesis as a building block due to its ability to form stable amide bonds. The Fmoc group serves as a protective moiety that can be easily removed under basic conditions, allowing for selective deprotection during the synthesis process. The presence of the hydroxyl group on the aromatic ring enhances the compound's solubility in polar solvents and can participate in hydrogen bonding, which may influence the overall conformation of peptides synthesized from it. Fmoc-D-4-Hydroxyphenylglycine is typically utilized in the field of medicinal chemistry and biochemistry for the development of peptide-based therapeutics and research applications. Its unique structural features contribute to its utility in creating peptides with specific functional properties, making it a valuable tool in synthetic organic chemistry.
Formula:C23H19NO5
InChI:InChI=1S/C23H19NO5/c25-15-11-9-14(10-12-15)21(22(26)27)24-23(28)29-13-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-12,20-21,25H,13H2,(H,24,28)(H,26,27)/t21-/m1/s1
InChI key:QBYSEGZHOGZXFO-OAQYLSRUSA-N
SMILES:C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@H](C4=CC=C(C=C4)O)C(=O)O
Synonyms:
  • Fmoc-DnTyr-OH
  • (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-(4-hydroxyphenyl)acetic acid
  • (R)-a-(Fmoc-amino)-4-hydroxybenzeneacetic acid
  • Fmoc-D-4-Hydroxyphenylglycine
  • REF DUPL: Fmoc-D-4-Hydroxyphenylglycine
  • (R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-2-(4-hydroxyphenyl)acetic acid
  • Nα-Fmoc-(4-hydroxy)-D-phenylglycine
  • Benzeneacetic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4-hydroxy-, (αR)-
Found 5 products.