CAS 178182-49-5

Methyl (2R,3R,3′R)-3′-[(2,6-dideoxy-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-4,5′,8′,9-tetrahydro-3,4′,9′,10-tetrahydroxy-7′-methoxy-5′,8′,9-trioxospiro[benzo[1,2-b:5,4-c′]dipyran-2(3H),2′(3′H)-naphtho[2,3-b]furan]-7-carboxylate

Description:

The chemical substance known as Methyl (2R,3R,3′R)-3′-[(2,6-dideoxy-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-4,5′,8′,9-tetrahydro-3,4′,9′,10-tetrahydroxy-7′-methoxy-5′,8′,9-trioxospiro[benzo[1,2-b:5,4-c′]dipyran-2(3H),2′(3′H)-naphtho[2,3-b]furan]-7-carboxylate, with CAS number 178182-49-5, is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as methoxy, hydroxyl, and carboxylate. This compound features a spirocyclic framework, indicative of its unique connectivity and stereochemistry, which contributes to its potential biological activity. The presence of sugar moieties suggests that it may exhibit properties relevant to glycosylation, influencing its solubility and interaction with biological systems. Additionally, the compound's multiple hydroxyl groups may enhance its reactivity and ability to form hydrogen bonds, potentially impacting its pharmacological profile. Overall, this substance represents a fascinating example of synthetic organic chemistry with potential applications in medicinal chemistry and biochemistry.

Formula: C₃₃H₃₀O₁₇

InChI: InChI=1S/C33H30O17/c1-10-23(36)15(44-3)9-18(46-10)48-30-22-25(38)20-13(34)8-14(43-2)24(37)21(20)27(40)29(22)50-33(30)17(35)7-12-5-11-6-16(31(41)45-4)47-32(42)19(11)26(39)28(12)49-33/h5-6,8,10,15,17-18,23,30,35-36,38-40H,7,9H2,1-4H3/t10-,15+,17+,18-,23-,30+,33+/m0/s1

InChI key: InChIKey=MLFZQFHGXSVTGX-MCTZXALVSA-N

SMILES: O([C@H]1[C@@]2(OC=3C1=C(O)C4=C(C3O)C(=O)C(OC)=CC4=O)OC=5C(C[C@H]2O)=CC6=C(C5O)C(=O)OC(C(OC)=O)=C6)[C@H]7C[C@@H](OC)[C@@H](O)[C@H](C)O7

Synonyms:

• Heliquinomycin
• Methyl (2R,3R,3′R)-3′-[(2,6-dideoxy-3-O-methyl-α-<span class="text-smallcaps">L</span>-ribo-hexopyranosyl)oxy]-4,5′,8′,9-tetrahydro-3,4′,9′,10-tetrahydroxy-7′-methoxy-5′,8′,9-trioxospiro[benzo[1,2-b:5,4-c′]dipyran-2(3H),2′(3′H)-naphtho[2,3-b]furan]-7-carboxylate
• NSC 702208
• Oxo-, Methyl Ester
• Rubymycin
• Spiro(benzo(1,2-b:5,4-c')dipyran-2(3H),2'(3'H)-naphtho(2,3-b)furan)-7-carboxylic acid, 4,5',8',9-tetrahydro-3'-((2,6-dideoxy-3-O-methylhexopyranosyl)oxy)-7'-methoxy-3,4',9',10-tetrahydroxy-5',8',9-tri
• Spiro[benzo[1,2-b:5,4-c′]dipyran-2(3H),2′(3′H)-naphtho[2,3-b]furan]-7-carboxylic acid, 3′-[(2,6-dideoxy-3-O-methyl-α-<span class="text-smallcaps">L</span>-ribo-hexopyranosyl)oxy]-4,5′,8′,9-tetrahydro-3,4′,9′,10-tetrahydroxy-7′-methoxy-5′,8′,9-trioxo-, methyl ester, (2R,3R,3′R)-
• methyl (2R,3R,3'R)-3-[(2,6-dideoxy-3-O-methylhexopyranosyl)oxy]-3',4,9,10'-tetrahydroxy-7-methoxy-5,8,9'-trioxo-4',5,8,9'-tetrahydro-3H,3'H-spiro[naphtho[2,3-b]furan-2,2'-pyrano[4,3-g]chromene]-7'-carboxylate
• Spiro[benzo[1,2-b:5,4-c′]dipyran-2(3H),2′(3′H)-naphtho[2,3-b]furan]-7-carboxylic acid, 3′-[(2,6-dideoxy-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-4,5′,8′,9-tetrahydro-3,4′,9′,10-tetrahydroxy-7′-methoxy-5′,8′,9-trioxo-, methyl ester, (2R,3R,3′R)-
• Methyl (2R,3R,3′R)-3′-[(2,6-dideoxy-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-4,5′,8′,9-tetrahydro-3,4′,9′,10-tetrahydroxy-7′-methoxy-5′,8′,9-trioxospiro[benzo[1,2-b:5,4-c′]dipyran-2(3H),2′(3′H)-naphtho[2,3-b]furan]-7-carboxylate

Heliquinomycin

CAS: 178182-49-5

Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.

Formula: C₃₃H₃₀O₁₇

Color and Shape: Solid

Molecular weight: 698.586

Ref: TM-T36748

Heliquinomycin

CAS: 178182-49-5

Formula: C₃₃H₃₀O₁₇

Purity: ≥ 80.0%

Color and Shape: Red powder

Molecular weight: 698.6

Ref: 7W-GL8551