CAS 1782573-78-7

ML 120B dihydrochloride

CAS: 1782573-78-7

MLN120B dihydrochloride: oral IKKβ inhibitor with 60 nM IC50, suppresses myeloma growth, used in arthritis research.

Formula: C₁₉H₁₇Cl₃N₄O₂

Color and Shape: Solid

Molecular weight: 439.72

Ref: TM-T39199

Ml 120b dihydrochloride

CAS: 1782573-78-7

Ml 120b dihydrochloride (Ml120b) is a small molecule drug that can be used to treat non-alcoholic steatohepatitis. Ml120b inhibits the nuclear factor kappa B (NF-κB) pathway by binding and inhibiting the IκB kinase, which is an enzyme involved in NF-κB activation. Ml120b also has other effects on the liver, such as modulating enzymes involved in lipid metabolism and inflammatory damage. Non-alcoholic fatty liver disease (NAFLD) is characterized by fat accumulation in hepatocytes, inflammation and damage to the liver cells. NAFLD can lead to nonalcoholic steatohepatitis, a more serious form of the disease with inflammation and damage to the liver cells. Diagnostic methods for NAFLD include ultrasound, CT scan and MRI, but these are expensive and not always accurate. As a result, tissue biopsies may be used to diagnose

Formula: C₁₉H₁₇Cl₃N₄O₂

Purity: Min. 95%

Molecular weight: 439.7 g/mol

Ref: 3D-HWC57378