CAS 178306-52-0

Benzenepropanoic acid,a-hydroxy-b-methoxy-b-phenyl-,(aS)-

Description:

Benzenepropanoic acid, α-hydroxy-β-methoxy-β-phenyl-, (αS)-, is a chiral compound characterized by its complex structure, which includes a benzene ring, a propanoic acid moiety, and hydroxyl and methoxy functional groups. This compound typically exhibits properties associated with both aromatic and aliphatic compounds, such as solubility in organic solvents and potential reactivity due to the presence of functional groups. The hydroxyl group contributes to its acidity, while the methoxy group can influence its electronic properties and steric hindrance. As a chiral molecule, it may exhibit different biological activities depending on its stereochemistry, making it of interest in pharmaceutical applications. The presence of multiple functional groups allows for various intermolecular interactions, such as hydrogen bonding, which can affect its physical properties, including melting and boiling points. Overall, this compound's unique structure and functional groups make it a subject of interest in organic chemistry and medicinal chemistry research.

Formula: C₁₆H₁₆O₄

Synonyms:

• (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid
• (S)-2-Hydroxyl -3-methoxy-3,3-diphenylpropanoic acid
• (S)-2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid
• Ambrisentan Intermediate-2
• Benzenepropanoic acid,a-hydroxy-b-methoxy-b-phenyl-,(aS)-
• (2S)-2-hydroxy-3-methoxy-3,3-diphenylpropanoic acid
• S-2-Hydroxy-3-methoxy-3
• ALST-3
• )-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid
• Benzenepropanoic acid, α-hydroxy-β-methoxy-β-phenyl-, (αS)-
• Ambrisentan Hydroxy Acid Impurity (S-Isomer)
• "(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid" Q: What is the CAS Number of
• Ambrisentan Hydroxy Acid Impurity
• 3-diphenylpropanoic acid
• Ambrisentan Related compound A
• Ambrisentan Hydroxy Impurity
• "(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid" Q: What is the storage condition of
• "(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid" Q: What are the applications of
• (
• "(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid"Q: What is
• S

(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid

CAS: 178306-52-0

Formula: C₁₆H₁₆O₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 272.30

Ref: 3B-H1568

Benzenepropanoic acid, α-hydroxy-β-methoxy-β-phenyl-, (αS)-

CAS: 178306-52-0

Formula: C₁₆H₁₆O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 272.2958

Ref: IN-DA0025XD

(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid

CAS: 178306-52-0

(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid

Purity: 98%

Molecular weight: 272.30g/mol

Ref: 54-OR75228

Ambrisentan Impurity 8

CAS: 178306-52-0

Formula: C₁₆H₁₆O₄

Molecular weight: 272.30

Ref: 4Z-A-318

(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid

Controlled Product

CAS: 178306-52-0

Formula: C₁₆H₁₆O₄

Color and Shape: Neat

Molecular weight: 272.30

Ref: 86-MM3756.01

(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid

Controlled Product

CAS: 178306-52-0

Impurity Ambrisentan Hydroxy Acid Impurity
Applications (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid is used in analytical studies for chiral discrimination of α-functionalized acids. Ambrisentan Hydroxy Acid Impurity
References Jain, N., et al.: Tetrahedron, 70, 4343 (2014)

Formula: C₁₆H₁₆O₄

Color and Shape: Neat

Molecular weight: 272.30

Ref: TR-H946110

Ambrisentan Hydroxy Acid Impurity (S-isomer)

CAS: 178306-52-0

Formula: C₁₆H₁₆O₄

Molecular weight: 272.30

Ref: ST-EA-CP-A15002

(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid

CAS: 178306-52-0

Formula: C₁₆H₁₆O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 272.3

Ref: 10-F212578

(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid

CAS: 178306-52-0

This is a crystalline form of the pyrimidine derivative (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic acid. The compound has been shown to have antiplatelet properties and is currently being developed as an antithrombotic agent. In vitro studies have shown that ambrisentan inhibits platelet aggregation, thromboxane synthesis, and leukocyte adhesion. It also reduces the levels of serum cholesterol and triglycerides in patients with chronic heart failure. Ambrisentan has been studied in clinical trials for the treatment of pulmonary hypertension associated with chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF).

Formula: C₁₆H₁₆O₄

Purity: Min. 95%

Molecular weight: 272.3 g/mol

Ref: 3D-FH33246