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CAS 178374-44-2

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2',3'-Dideoxy-3'-fluoro-a-D-uridine

Description:
2',3'-Dideoxy-3'-fluoro-α-D-uridine, commonly referred to as FDDU, is a nucleoside analog that exhibits antiviral properties, particularly against certain viruses such as HIV. This compound is characterized by the absence of a hydroxyl group at the 2' and 3' positions of the ribose sugar, which contributes to its mechanism of action as an inhibitor of viral replication. The presence of a fluorine atom at the 3' position enhances its stability and bioactivity compared to its natural counterparts. FDDU is typically studied for its potential therapeutic applications in antiviral treatments, and its structure allows it to interfere with nucleic acid synthesis in viral pathogens. Additionally, its unique chemical properties make it a subject of interest in medicinal chemistry and drug development. As with many nucleoside analogs, understanding its pharmacokinetics, toxicity, and efficacy is crucial for evaluating its potential as a therapeutic agent.
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