CAS 1784-03-8

L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)

Description:

L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1) is a chemical compound that features a combination of an amino acid, L-arginine, and a sulfonyl group attached to a methylphenyl moiety. This compound is characterized by its basic amino acid structure, which includes a guanidinium group, contributing to its role in various biological processes, such as protein synthesis and nitric oxide production. The presence of the methyl ester indicates that it is a derivative of L-arginine, which can enhance its solubility and bioavailability. The hydrochloride form suggests that it is a salt, which typically improves stability and handling properties. This compound may exhibit various pharmacological activities, including potential roles in cardiovascular health and immune function. Its sulfonyl group can also influence its reactivity and interaction with biological targets. Overall, L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride is of interest in both biochemical research and potential therapeutic applications.

Formula: C₁₄H₂₂N₄O₄S·ClH

InChI: InChI=1S/C14H22N4O4S.ClH/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16;/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17);1H/t12-;/m0./s1

InChI key: InChIKey=JIQFFACVQXXHMY-YDALLXLXSA-N

SMILES: S(N[C@@H](CCCNC(=N)N)C(OC)=O)(=O)(=O)C1=CC=C(C)C=C1.Cl

Synonyms:

• <span class="text-smallcaps">L</span>-Arginine, N²-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)
• <span class="text-smallcaps">L</span>-Arginine, N²-[(4-methylphenyl)sulfonyl]-, methyl ester, monohydrochloride
• Arginine, N²-(p-tolylsulfonyl)-, methyl ester, monohydrochloride, <span class="text-smallcaps">L</span>-
• N-alpha-Toluenesulfonylarginine methyl ester hydrochloride
• N-alpha-Tosyl-L-arginine methyl ester hydrochloride
• N-p-Tosyl-L-arginine methyl ester hydrochloride
• N-α-p-Tosyl-L-arginine methyl ester hydrochloride
• N^α-Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• Nalpha-(4-Toluenesulfonyl)-L-Arginine Methyl Ester Hydrochloride
• Tame
• Tos-Arg-OMe . HCl
• Tos-Arg-OMe・HCl
• Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• Tosylarginine methyl ester hydrochloride
• methyl N5-(diaminomethylidene)-N2-[(4-methylphenyl)sulfonyl]-L-ornithinate hydrochloride
• methyl N5-(diaminomethylidene)-N2-[(4-methylphenyl)sulfonyl]ornithinate hydrochloride
• na-P-tosyl-L-arginine methyl*ester hydrochloride
• α-N-Tosyl-<span class="text-smallcaps">L</span>-arginine methyl ester hydrochloride
• L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)
• α-N-Tosyl-L-arginine methyl ester hydrochloride
• Nα-Tosyl-L-arginine methyl ester hydrochloride
• L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, monohydrochloride

Nα-Tosyl-L-arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

Formula: C₁₄H₂₂N₄O₄S·HCl

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 378.87

Ref: 3B-T0330

Tos-Arg-OMe · HCl

CAS: 1784-03-8

A good substrate for trypsin, thrombin, and urokinase as well as for plasma and glandular kallikreins. By competing for the arginine-binding site in the reactive center of proteases, L-TAME is also able to act as a reversible inhibitor. It suppresses, e.g., the TNF secretion of human leukocytes which is evidently dependent upon the action of serine proteases.

Formula: C₁₄H₂₂N₄O₄S·HCl

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 378.88

Ref: 01-4002251

L-Arginine, N2-[(4-methylphenyl)sulfonyl]-, methyl ester, hydrochloride (1:1)

CAS: 1784-03-8

Formula: C₁₄H₂₃ClN₄O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 378.8748

Ref: IN-DA0025ZQ

TAME hydrochloride

CAS: 1784-03-8

TAME hydrochloride (Tos-Arg-OMe HCl) is a kind od amino acid derivatives.

Formula: C₁₄H₂₃ClN₄O₄S

Purity: 99.11% - 99.21%

Color and Shape: White Fine Crystalline Powder

Molecular weight: 378.87

Ref: TM-T1731

TAME hydrochloride

CAS: 1784-03-8

TAME hydrochloride

Purity: ≥95%

Molecular weight: 378.87g/mol

Ref: 54-BUP17017

N-α-p-Tosyl-L-Arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

N-α-p-Tosyl-L-Arginine Methyl Ester Hydrochloride

Purity: 98%

Molecular weight: 378.87g/mol

Ref: 54-OR1014507

TAME Hydrochloride

CAS: 1784-03-8

Formula: C₁₄H₂₂N₄O₄S·HCl

Purity: ≥ 98.0%

Color and Shape: White to almost white powder

Molecular weight: 378.87

Ref: 7W-GM4942

N-α-Tosyl-L-arginine methyl ester hydrochloride

CAS: 1784-03-8

N-alpha-Tosyl-L-arginine methyl ester hydrochloride is a potent inhibitor of the serine protease leishmania. It inhibits the enzyme by binding to its active site and interfering with the enzymatic reaction. This drug has been shown to be effective in treating bladder infections caused by leishmania, although it can cause a decrease in responsiveness in an animal model. N-alpha-Tosyl-L-arginine methyl ester hydrochloride also has anti-HIV activities, which may be due to its ability to inhibit HIV replication. The drug is most likely absorbed through the apical surface of the bladder epithelium and then diffuses into the extracellular space, where it inhibits key enzymes involved in viral replication.

Formula: C₁₄H₂₂N₄O₄S·HCl

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 378.88 g/mol

Ref: 3D-FT55915

TAME hydrochloride

CAS: 1784-03-8

Purity: 98%

Molecular weight: 378.87

Ref: 10-M03112

N-4-Tosyl-L-arginine Methyl Ester Hydrochloride

CAS: 1784-03-8

Applications N-4-Tosyl-L-arginine Methyl Ester Hydrochloride acts as a synthetic substrate of serine proteases and thus is used to determine serine proteases from diverse organic sources.
References Hummel, B. et al.: Can. J. Biochem. Physiol., 37, 1393 (1959); Matsuda, Y. et al.: J. Biochem. 80, 671 (1976);

Formula: C₁₄H₂₃ClN₄O₄S

Color and Shape: Neat

Molecular weight: 378.87

Ref: TR-T570000

TAME hydrochloride

CAS: 1784-03-8

Tos-Arg-OMe • HCl is a peptide that has been shown to modulate the responsiveness of cells to sodium channels. Tos-Arg-OMe • HCl may also be useful as an anti-cancer drug, as it inhibits cancer cell growth and induces apoptosis. This peptide has been shown to be an effective treatment for HIV infection by inhibiting viral replication. It also reduces inflammation and prevents the development of other opportunistic infections in animal models.

Formula: C₁₄H₂₂N₄O₄S·ClH

Purity: Min. 95%

Molecular weight: 378.87 g/mol

Ref: 3D-STR-3003