CAS 17857-14-6

(3-CARBOXYPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE

Description:

(3-Carboxypropyl)triphenylphosphonium bromide is a quaternary ammonium salt characterized by its triphenylphosphonium cation and a carboxypropyl group. This compound typically appears as a white to off-white solid and is soluble in polar solvents such as water and methanol, owing to the presence of the carboxylic acid functional group. The triphenylphosphonium moiety contributes to its lipophilicity, making it useful in various biochemical applications, including as a mitochondrial targeting agent. The bromide anion serves as a counterion, influencing the compound's solubility and reactivity. This substance is often utilized in organic synthesis and medicinal chemistry, particularly in the development of phosphonium-based reagents and catalysts. Its ability to facilitate the transfer of electrons and its role in biological systems, such as in the transport of drugs or other therapeutic agents, are of significant interest in research. Safety data should be consulted for handling and storage, as with all chemical substances.

Formula: C₂₂H₂₂BrO₂P

InChI: InChI=1/C22H21O2P.BrH/c23-22(24)17-10-18-25(19-11-4-1-5-12-19,20-13-6-2-7-14-20)21-15-8-3-9-16-21;/h1-9,11-16H,10,17-18H2;1H

SMILES: c1ccc(cc1)[P+](CCCC(=O)[O-])(c1ccccc1)c1ccccc1.Br

Synonyms:

• 3-Carboxypropyltriphenylphosphonium bromide

(3-Carboxypropyl)triphenylphosphonium Bromide

CAS: 17857-14-6

Formula: C₂₂H₂₂BrO₂P

Purity: >95.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 429.29

Ref: 3B-C1635

(3-Carboxypropyl)triphenylphosphonium bromide, 97%

CAS: 17857-14-6

Reactant for preparation of Piperamide analogs as histone deacetylase (HDAC) inhibitors with antitumor activity, Boron-containing benzoxaboroles as antimalarial agents, Methyl alkenyl quinolones as antimycobacterial agents, Solandelactone E via Sharpless epoxidation, Taber cyclopropanation, chemosel

Formula: C₂₂H₂₂BrO₂P

Purity: 97%

Color and Shape: Powder, White

Molecular weight: 429.29

Ref: 02-A19302

Phosphonium, (3-​carboxypropyl)​triphenyl-​, bromide (1:1)

CAS: 17857-14-6

Formula: C₂₂H₂₂BrO₂P

Purity: 97%

Color and Shape: Solid

Molecular weight: 429.2866

Ref: IN-DA00265V

(3-Carboxyprop-1-yl)(triphenyl)phosphonium bromide

CAS: 17857-14-6

(3-Carboxyprop-1-yl)(triphenyl)phosphonium bromide

Formula: C₂₂H₂₂O₂P·Br

Purity: 98%

Color and Shape: white to off-white solid

Molecular weight: 429.29g/mol

Ref: 54-OR0912

3-Carboxypropyltriphenylphosphonium bromide

CAS: 17857-14-6

Formula: HO₂C(CH₂)₃P(C₆H₅)₃Br

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 429.30

Ref: 7W-GK5096

3-Carboxypropyltriphenylphosphonium bromide

CAS: 17857-14-6

Purity: 97%

Molecular weight: 428.054

Ref: 10-F986534

(3-Carboxypropyl)triphenylphosphonium Bromide

Controlled Product

CAS: 17857-14-6

Applications (3-Carboxypropyl)triphenylphosphonium Bromide is a reagent used in the preparation of sphingosine 1-phosphate-1 receptor antagonists. Also used in the synthesis of mitochondrial vitamin E metabolites and other mitochondrial targets in the study of mitochodrial functions. Also used in the preparation of benzosuberene analogs that inhibit tubulin assembly and demonstrate cytotoxicity.
References Wang, X. et al.: J. Mat. Chem. B. Mat. Biol. Med.,1, 5143 (2013); Tanpure, R. et al.: MedChemComm., 3, 720 (2012);

Formula: C₂₂H₂₂BrO₂P

Color and Shape: Neat

Molecular weight: 429.09

Ref: TR-C181500