CAS 178603-73-1

biotinyl-asp-glu-val-aspartin-1-al

Description:

Biotinyl-asp-glu-val-aspartin-1-al, identified by its CAS number 178603-73-1, is a synthetic peptide that incorporates biotin, a vitamin known for its role in cellular metabolism and as a cofactor for carboxylase enzymes. This compound features a sequence of amino acids, including aspartic acid (Asp), glutamic acid (Glu), and valine (Val), which contribute to its structural and functional properties. The presence of biotin allows for easy conjugation to various biomolecules, making it valuable in biochemical applications such as affinity purification, drug delivery, and as a probe in molecular biology techniques. The peptide's structure may influence its solubility, stability, and interaction with biological targets. Additionally, the incorporation of specific amino acids can affect its biological activity and potential therapeutic applications. Overall, biotinyl-asp-glu-val-aspartin-1-al serves as a versatile tool in research and biotechnology, leveraging the unique properties of both biotin and the peptide sequence.

Formula: C₂₈H₄₂N₆O₁₂S

InChI: InChI=1/C28H42N6O12S/c1-13(2)23(27(45)29-14(11-35)9-21(39)40)33-25(43)15(7-8-20(37)38)31-26(44)16(10-22(41)42)30-19(36)6-4-3-5-18-24-17(12-47-18)32-28(46)34-24/h11,13-18,23-24H,3-10,12H2,1-2H3,(H,29,45)(H,30,36)(H,31,44)(H,33,43)(H,37,38)(H,39,40)(H,41,42)(H2,32,34,46)/t14-,15-,16-,17-,18-,23-,24-/m0/s1

SMILES: CC(C)[C@@H](C(=N[C@@H](CC(=O)O)C=O)O)N=C([C@H](CCC(=O)O)N=C([C@H](CC(=O)O)N=C(CCCC[C@H]1[C@@H]2[C@H](CS1)N=C(N2)O)O)O)O

Synonyms:

• Biotinyl-Asp-Glu-Val-Asp-aldehyde (pseudo acid)
• N-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}-L-alpha-aspartyl-L-alpha-glutamyl-N-[(2S)-1-carboxy-3-oxopropan-2-yl]-L-valinamide
• Biotin-Devd-Cho

L-Valinamide, N-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-L-α-aspartyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-

CAS: 178603-73-1

Formula: C₂₈H₄₂N₆O₁₂S

Molecular weight: 686.7311

Ref: IN-DA002660

Biotinyl-Asp-Glu-Val-Asp-H (aldehyde)

CAS: 178603-73-1

Biotinyl-Asp-Glu-Val-Asp-H (aldehyde) is a peptide that has been used as a research tool for the study of ion channels and protein interactions. It has an affinity for the receptor site on cell membranes, which may be due to its ability to act as an inhibitor or ligand. This peptide has been shown to bind to the acetylcholine receptor, which is involved in neurotransmission and nerve function. Biotinyl-Asp-Glu-Val-Asp-H (aldehyde) binds with high specificity to the receptor site and blocks the binding of acetylcholine, inhibiting nerve transmission.

Formula: C₂₈H₄₂N₆O₁₂S

Purity: Min. 95%

Molecular weight: 686.73 g/mol

Ref: 3D-IBA-3173-V

Biotinyl-Asp-Glu-Val-Asp-aldehyde (pseudo acid)

CAS: 178603-73-1

Biotinyl-Asp-Glu-Val-Asp-aldehyde (pseudo acid) is a biotinylated amino acid, which can be used to study the affinity of caspases and other proteases. Biotin binds to the peptide through an amide bond and the amino group on the biotin molecule reacts with reactive groups on proteins, such as lysine, cysteine, histidine, or arginine. This reaction leads to the formation of a stable link between biotin and the target protein. The biotinylated peptide can then be purified from a sample by using an affinity chromatography column that has been pre-coated with streptavidin.
Biotin is not toxic because it does not bind to DNA.

Formula: C₂₈H₄₂N₆O₁₂S

Purity: Min. 95%

Molecular weight: 686.73 g/mol

Ref: 3D-FB111057