CAS 178603-78-6: interleukin-1B (1L-1B) converting*enzyme (ice) in

Description: Interleukin-1β converting enzyme (ICE), also known as caspase-1, is a crucial enzyme involved in the inflammatory response and the processing of pro-inflammatory cytokines. It plays a significant role in the activation of interleukin-1β (IL-1β) and interleukin-18 (IL-18), which are key mediators in immune responses. ICE is a cysteine protease that belongs to the caspase family, characterized by its ability to cleave specific peptide bonds in target proteins, leading to their activation or inactivation. The enzyme is typically found in the cytoplasm and is activated in response to various stimuli, including pathogen-associated molecular patterns. Dysregulation of ICE activity has been implicated in several inflammatory diseases, making it a target for therapeutic intervention. The CAS number 178603-78-6 specifically identifies a compound related to ICE, which may be used in research or drug development contexts. Overall, ICE is essential for maintaining immune homeostasis and mediating inflammatory processes.

Formula: C₂₄H₃₃ClN₄O₈

Synonyms:

• Ac-Tyr-Val-Ala-Asp-chloromethylketone
• Ac-Yvad-Cmk

Ac-Tyr-Val-Ala-Asp-chloromethylketone

CAS: 178603-78-6

Cell-permeable, irreversible inhibitor of caspase-1 (ICE). N.Rouquet et al. showed that Ac-YVAD-CMK is a potent …

• Formula: C₂₄H₃₃ClN₄O₈
• Purity: 97.9%
• Color and Shape: White Lyophilisate
• Molecular weight: 541.01

L-Alaninamide, N-acetyl-L-tyrosyl-L-valyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-

CAS: 178603-78-6

• Formula: C₂₄H₃₃ClN₄O₈
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 540.9938199999997

Ac-YVAD-CMK

CAS: 178603-78-6

Ac-YVAD-CMK: Irreversible Caspase-1 inhibitor; halts pyroptosis, IL-1β/IL-18; neuroprotective and anti-inflammatory.

• Formula: C₂₄H₃₃ClN₄O₈
• Purity: 97.08% - 99.49%
• Color and Shape: Solid
• Molecular weight: 540.99

Ac-YVAD-CMK

CAS: 178603-78-6

• Purity: 99.49%
• Molecular weight: 540.99g/mol

Caspase-1 Inhibitor II

CAS: 178603-78-6

Applications Caspase-1 Inhibitor II is an inhibitor of caspase-1, caspase-4, and caspase-5.

• Formula: C₂₄H₃₃ClN₄O₈
• Color and Shape: Neat
• Molecular weight: 540.99

Ac-Tyr-Val-Ala-Asp-CH2Cl

CAS: 178603-78-6

Please enquire for more information about Ac-Tyr-Val-Ala-Asp-CH2Cl including the price, delivery time and more detailed …

• Formula: C₂₄H₃₃N₄O₈Cl
• Purity: Min. 95%
• Molecular weight: 540.99 g/mol

Ac-Tyr-Val-Lys-Asp-H (aldehyde)

CAS: 178603-78-6

Please enquire for more information about Ac-Tyr-Val-Lys-Asp-H (aldehyde) including the price, delivery time and more …

• Formula: C₂₆H₃₉N₅O₈
• Purity: Min. 95%

Ac-Tyr-Val-Ala-Asp-chloromethylketone

CAS: 178603-78-6

Please enquire for more information about Ac-Tyr-Val-Ala-Asp-chloromethylketone including the price, delivery time and more detailed …

• Formula: C₂₄H₃₃ClN₄O₈
• Purity: Min. 95%
• Molecular weight: 540.99 g/mol