CAS 1788-10-9

4-Acetylbenzenesulfonyl chloride

Description:

4-Acetylbenzenesulfonyl chloride, with the CAS number 1788-10-9, is an organic compound characterized by the presence of both an acetyl group and a sulfonyl chloride functional group. It appears as a white to light yellow crystalline solid and is known for its reactivity, particularly due to the sulfonyl chloride moiety, which can readily participate in nucleophilic substitution reactions. This compound is soluble in organic solvents such as dichloromethane and chloroform but is generally insoluble in water. It is commonly used as a reagent in organic synthesis, particularly in the preparation of sulfonamides and other sulfonyl derivatives. The compound is sensitive to moisture and should be handled with care, as it can release hydrochloric acid upon hydrolysis. Additionally, it is important to note that appropriate safety measures should be taken when working with this substance, as it can be corrosive and irritating to the skin, eyes, and respiratory system.

Formula: C₈H₇ClO₃S

InChI: InChI=1/C8H7ClO3S/c1-6(10)7-2-4-8(5-3-7)13(9,11)12/h2-5H,1H3

InChI key: InChIKey=FXVDNCRTKXMSEZ-UHFFFAOYSA-N

SMILES: S(Cl)(=O)(=O)C1=CC=C(C(C)=O)C=C1

Synonyms:

• 4-Acetylbenzene-1-sulfonyl chloride
• 4-Acetylbenzensulfonyl chloride
• 4-Acetylphenylsulfonyl chloride
• Acetophenone-4-Sulfonyl Chloride
• Akos Bb-9467
• Benzenesulfonyl chloride, 4-acetyl-
• Benzenesulfonyl chloride, p-acetyl-
• NSC 104128
• P-Acetyl-Benzenesulfonyl Chloride
• Timtec-Bb Sbb005811
• p-Acetylbenzenesulfonyl chloride

4-Acetylbenzenesulfonyl chloride

CAS: 1788-10-9

Formula: C₈H₇ClO₃S

Purity: 95%

Color and Shape: Chunks,Powder

Molecular weight: 218.65

Ref: 10-F015077

Benzenesulfonyl chloride, 4-​acetyl-

CAS: 1788-10-9

Formula: C₈H₇ClO₃S

Purity: 95%

Color and Shape: Solid

Molecular weight: 218.6574

Ref: IN-DA0026C2

4-Acetylbenzenesulfonyl chloride

CAS: 1788-10-9

4-Acetylbenzenesulfonyl chloride

Purity: 92%

Molecular weight: 218.66g/mol

Ref: 54-OR96764

4-Acetylbenzenesulfonyl chloride

CAS: 1788-10-9

Formula: C₈H₇ClO₃S

Molecular weight: 218.66

Ref: 7W-GK5617

4-Acetylbenzenesulfonyl Chloride

Controlled Product

CAS: 1788-10-9

Applications 4-Acetylbenzenesulfonyl Chloride is used as one of the substances for mutagenic and carcinogenic risk assessment of carboxylic and sulfonic acid halides as drug impurities. Also, acts as a reagent for the synthesis of (+)-Dehydroabietylamine derivatives which are targeted for triple-negative breast cancer treatment.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Amberg, A., et al.: Org. Process Res. Dev., 19, 1495 (2015); Ling, T., et al.: Eur. J. Med. Chem., 102, 13, (2015)

Formula: C₈H₇ClO₃S

Color and Shape: Neat

Molecular weight: 218.66

Ref: TR-A145115

4-Acetylbenzenesulfonyl chloride

CAS: 1788-10-9

4-Acetylbenzenesulfonyl chloride is a linker molecule that can be used for the synthesis of bioactive molecules. The 4-acetylbenzenesulfonyl chloride can be used to introduce active methylene groups into molecules, which is important for bioactivity. This compound has been shown to have a number of cancer-related applications, and has been shown to be effective in the treatment of insulin resistance.

Formula: C₈H₇ClO₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 218.66 g/mol

Ref: 3D-FA58809