5-Iododeoxyuridine-ced phosphoramidite is a chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features a deoxyuridine base modified with an iodine atom at the 5-position, which enhances its reactivity and incorporation into DNA strands. The phosphoramidite group facilitates the stepwise synthesis of oligonucleotides through solid-phase synthesis techniques, allowing for the efficient addition of nucleotides. The presence of the iodine atom can also impart unique properties to the resulting oligonucleotides, such as increased stability or altered binding characteristics. This compound is typically utilized in research and therapeutic applications, including gene therapy and the development of antisense oligonucleotides. As with many phosphoramidites, it is crucial to handle this substance with care, as it may be sensitive to moisture and air, which can affect its reactivity and overall performance in synthetic applications.

5-iododeoxyuridine-ced phosphoramidite  for abi

178925-48-9: 5-Iododeoxyuridine-ced phosphoramidite is a chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features a deoxyuridine base modified with an iodine atom at the 5-position, which enhances its reactivity and incorporation into DNA strands. The phosphoramidite group facilitates the stepwise synthesis of oligonucleotides through solid-phase synthesis techniques, allowing for the efficient addition of nucleotides. The presence of the iodine atom can also impart unique properties to the resulting oligonucleotides, such as increased stability or altered binding characteristics. This compound is typically utilized in research and therapeutic applications, including gene therapy and the development of antisense oligonucleotides. As with many phosphoramidites, it is crucial to handle this substance with care, as it may be sensitive to moisture and air, which can affect its reactivity and overall performance in synthetic applications.

5'-O-DMTr-2'-deoxy-5-iodouridine-3'-CED Phosphoramidite

<p>2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite is a synthetic nucleoside that has shown anticancer and antiviral properties. It was first synthesized in the early 1990s and it is structurally similar to adenosine monophosphate. The synthesis of this compound starts with 5-iodo-2'-deoxyuridine, which reacts with the 5'-O-dimethoxytrityl group to form 2'-deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite. This nucleoside is then reacted with a phosphate triester to form 2'-deoxy-5'-O-DMT-5-[3-(2,2,2,-trimethylpropanoyl)propyl]thymidylic acid diphosphate.</p>

CAS 178925-48-9

5-iododeoxyuridine-ced phosphoramidite for abi

5'-O-DMTr-2'-deoxy-5-iodouridine-3'-CED Phosphoramidite

Ref: TM-TNU0676

2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite

Ref: 3D-PD08600