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CAS 178979-85-6

:

Capravirine

Description:
Capravirine is an antiretroviral medication primarily used in the treatment of HIV infection. It belongs to the class of non-nucleoside reverse transcriptase inhibitors (NNRTIs), which function by inhibiting the reverse transcriptase enzyme, thereby preventing the replication of the virus. Capravirine is characterized by its ability to maintain activity against certain strains of HIV that have developed resistance to other NNRTIs. The compound exhibits a unique chemical structure that contributes to its pharmacological properties, including its binding affinity to the target enzyme. It is typically administered orally and has a favorable pharmacokinetic profile, allowing for once-daily dosing in some treatment regimens. As with other antiretroviral agents, potential side effects may include rash, gastrointestinal disturbances, and liver enzyme elevations. Ongoing research continues to evaluate its efficacy and safety in various patient populations, particularly in those with multi-drug resistant HIV strains. Overall, Capravirine represents a valuable option in the evolving landscape of HIV treatment.
Formula:C20H20Cl2N4O2S
InChI:InChI=1/C20H20Cl2N4O2S/c1-12(2)18-19(29-16-8-14(21)7-15(22)9-16)26(10-13-3-5-24-6-4-13)17(25-18)11-28-20(23)27/h3-9,12H,10-11H2,1-2H3,(H2,23,27)
InChI key:InChIKey=YQXCVAGCMNFUMQ-UHFFFAOYSA-N
SMILES:C(N1C(SC2=CC(Cl)=CC(Cl)=C2)=C(C(C)C)N=C1COC(N)=O)C=3C=CN=CC3
Synonyms:
  • 1H-Imidazole-2-methanol, 5-((3,5-dichlorophenyl)thio)-4-(1-methylethyl)-1-(4-pyridinylmethyl)-, carbamate (ester)
  • S 1153
  • AG 1549
  • 5-((3,5-Dichlorophenyl)thio)-4-isopropyl-1-(4-pyridylmethyl)imidazole-2-methanol carbamate (ester)
  • {5-[(3,5-dichlorophenyl)sulfanyl]-4-(propan-2-yl)-1-(pyridin-4-ylmethyl)-1H-imidazol-2-yl}methyl carbamate
  • 1H-Imidazole-2-methanol, 5-[(3,5-dichlorophenyl)thio]-4-(1-methylethyl)-1-(4-pyridinylmethyl)-, carbamate (ester)
  • AG 1549
  • 1H-Imidazole-2-methanol, 5-[(3,5-dichlorophenyl)thio]-4-(1-methylethyl)-1-(4-pyridinylmethyl)-, 2-carbamate
  • Capravirine
  • UNII-VHC779598X
  • See more synonyms
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  • Capravirine
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    Capravirine

    CAS:
    Capravirine, a non-nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
    Formula:C20H20Cl2N4O2S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:451.37

    Ref: TM-T26946