CAS 179070-90-7

N-hydroxy-6-(trifluoromethoxy)-1,3-benzothiazol-2-amine

Description:

N-hydroxy-6-(trifluoromethoxy)-1,3-benzothiazol-2-amine is a chemical compound characterized by its unique structural features, which include a benzothiazole core, a hydroxylamine functional group, and a trifluoromethoxy substituent. The presence of the trifluoromethoxy group enhances its lipophilicity and may influence its biological activity, making it of interest in medicinal chemistry. The hydroxylamine moiety can participate in various chemical reactions, including oxidation and conjugation, which may be relevant for its reactivity and potential applications. This compound is typically studied for its potential use in pharmaceuticals, particularly in the development of agents with antimicrobial or anticancer properties. Its molecular structure suggests that it may exhibit specific interactions with biological targets, which can be explored through further research. Additionally, the compound's stability, solubility, and reactivity are influenced by the presence of the trifluoromethoxy group, making it a subject of interest in both synthetic and applied chemistry contexts.

Formula: C₈H₅F₃N₂O₂S

InChI: InChI=1/C8H5F3N2O2S/c9-8(10,11)15-4-1-2-5-6(3-4)16-7(12-5)13-14/h1-3,14H,(H,12,13)

SMILES: c1cc2c(cc1OC(F)(F)F)sc(n2)NO

2-Benzothiazolamine, N-hydroxy-6-(trifluoromethoxy)-

CAS: 179070-90-7

Formula: C₈H₅F₃N₂O₂S

Color and Shape: Solid

Molecular weight: 250.1977

Ref: IN-DA0026S4

N-Hydroxy Riluzole

CAS: 179070-90-7

Formula: C₈H₅F₃N₂O₂S

Color and Shape: Pale Pink Solid

Molecular weight: 250.20

Ref: 4Z-R-144

N-hydroxy Riluzole

CAS: 179070-90-7

N-hydroxy Riluzole, a metabolite of riluzole, is mainly produced by CYP1A2 in human liver.

Formula: C₈H₅F₃N₂O₂S

Color and Shape: Solid

Molecular weight: 250.20

Ref: TM-T35919

N-Hydroxy Riluzole

Controlled Product

CAS: 179070-90-7

Applications A metabolite of Riluzole.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Distlerath, L., et al.: J. Biol. Chem., 260, 9057 (1985), Back, D., et al.: Br. J. Clin. Pharmacol., 28, 166 (1989), Sattler, M., et al.: Drug Metab. Dispos., 20, 753 (1992), Andersson, T., et al.: Br. J. Clin. Pharmacol., 36, 521 (1993),

Formula: C₈H₅F₃N₂O₂S

Color and Shape: Neat

Molecular weight: 250.20

Ref: TR-H953330

N-Hydroxy-6-(trifluoromethoxy)-2-benzothiazolamine

CAS: 179070-90-7

N-Hydroxy-6-(trifluoromethoxy)-2-benzothiazolamine (NHTB) is a drug that has been shown to have clinical use as an anticonvulsant. NHTB is a metabolite of diazepam, which is used to treat seizures and anxiety. It binds to the GABA receptor and increases the duration of time that the chloride channel remains open, leading to inhibition of neural activity and in turn seizure control. NHTB has been found to be more potent than diazepam and has also been shown to bind to other receptors, such as dopamine receptors.

Formula: C₈H₅F₃N₂O₂S

Purity: Min. 95%

Molecular weight: 250.2 g/mol

Ref: 3D-IH59728

N-Hydroxy Riluzole

CAS: 179070-90-7

Formula: C₈H₅F₃N₂O₂S

Molecular weight: 250.2

Ref: ST-EA-CP-R14008