CAS 179232-29-2

Methyl 4-bromo-2-fluorobenzoate

Description:

Methyl 4-bromo-2-fluorobenzoate is an organic compound characterized by its aromatic structure, which includes a benzene ring substituted with both a bromine and a fluorine atom, as well as an ester functional group. The presence of the bromine and fluorine atoms introduces significant electronegativity, influencing the compound's reactivity and polarity. This compound is typically a colorless to pale yellow liquid or solid, depending on its purity and temperature. It is soluble in organic solvents such as ethanol and dichloromethane but has limited solubility in water due to its hydrophobic aromatic structure. Methyl 4-bromo-2-fluorobenzoate is often utilized in synthetic organic chemistry as an intermediate for the preparation of various pharmaceuticals and agrochemicals. Its unique substitution pattern can lead to interesting chemical behavior, making it a valuable compound for research and development in medicinal chemistry. Safety precautions should be observed when handling this compound, as it may pose health risks if ingested or inhaled.

Formula: C₈H₆BrFO₂

InChI: InChI=1/C8H6BrFO2/c1-12-8(11)6-3-2-5(9)4-7(6)10/h2-4H,1H3

SMILES: COC(=O)c1ccc(cc1F)Br

Synonyms:

• 4-Bromo-2-Fluorobenzoic Acid Methyl Ester

Benzoic acid, 4-bromo-2-fluoro-, methyl ester

CAS: 179232-29-2

Formula: C₈H₆BrFO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 233.0344

Ref: IN-DA0026VP

Methyl 4-Bromo-2-fluorobenzoate

CAS: 179232-29-2

Formula: C₈H₆BrFO₂

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 233.04

Ref: 3B-M3229

Enzalutamide Impurity C

CAS: 179232-29-2

Formula: C₈H₆BrFO₂

Molecular weight: 233.04

Ref: 4Z-E-068008

Methyl 4-bromo-2-fluorobenzoate

CAS: 179232-29-2

Methyl 4-bromo-2-fluorobenzoate

Formula: C₈H₆BrFO₂

Purity: 97%

Color and Shape: white solid

Molecular weight: 233.03g/mol

Ref: 54-PC200410

Enzalutamide EP Impurity C

CAS: 179232-29-2

Formula: C₈H₆BrFO₂

Molecular weight: 233.03

Ref: ST-EA-CP-E16003

Methyl 4-bromo-2-fluorobenzoate

CAS: 179232-29-2

Formula: C₈H₆BrFO₂

Purity: 97%

Color and Shape: Crystalline Powder

Molecular weight: 233.036

Ref: 10-F069970

4-Bromo-2-fluorobenzoic Acid Methyl Ester

Controlled Product

CAS: 179232-29-2

Applications 4-Bromo-2-fluorobenzoic Acid Methyl Ester is the methyl ester derivative of 4-Bromo-2-fluorobenzoic Acid (B684620) and is used as a reagent in the synthesis of aminopyridyl-based inhibitors targeting Trypanosoma cruzi CYP51 as anti-Chagas agents.
References Choi, J.Y., et al.: J. Med. Chem., 56, 7651 (2013)

Formula: C₈H₆BrFO₂

Color and Shape: Neat

Molecular weight: 233.03

Ref: TR-B683335

4-Bromo-2-fluorobenzoic acid methyl ester

CAS: 179232-29-2

4-Bromo-2-fluorobenzoic acid methyl ester is a synthetic chemical that is used as a drug substance in the synthesis of pharmaceuticals. It is also a reagent for organic synthesis, specifically cross coupling reactions. 4-Bromo-2-fluorobenzoic acid methyl ester can be used to introduce an alkyl group into a molecule, which can then be used in other synthetic reactions. This chemical has been shown to inhibit prolyl hydroxylase (PHD), which is an enzyme that catalyzes the conversion of proline to hydroxyproline. 4-Bromo-2-fluorobenzoic acid methyl ester also inhibits the Bcl-2 family proteins, including bcl2, bclxl and bax, which are known to play a role in apoptosis. 4-Bromo-2-fluorobenzoic acid methyl ester

Formula: C₈H₆BrFO₂

Purity: Min. 95%

Molecular weight: 233.03 g/mol

Ref: 3D-FB74969