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CAS 179264-81-4

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TRITRPTICIN

Description:
Tritrpticin, with the CAS number 179264-81-4, is a synthetic antimicrobial peptide that exhibits notable antibacterial properties. It is derived from the natural peptide tritrpticin, which is known for its effectiveness against a range of Gram-positive and Gram-negative bacteria. The structure of tritrpticin typically features a sequence of amino acids that contribute to its ability to disrupt bacterial cell membranes, leading to cell lysis and death. This peptide is characterized by its cationic nature, which enhances its interaction with negatively charged bacterial membranes. Additionally, tritrpticin has been studied for its potential applications in medicine, particularly in the development of new antibiotics to combat antibiotic-resistant strains of bacteria. Its stability and efficacy make it a subject of interest in pharmaceutical research, although further studies are necessary to fully understand its mechanisms of action and potential therapeutic uses. Overall, tritrpticin represents a promising avenue in the search for novel antimicrobial agents.
Formula:C96H132N28O14
Synonyms:
  • VAL-ARG-ARG-PHE-PRO-TRP-TRP-TRP-PRO-PHE-LEU-ARG-ARG
  • TRITRPTICIN
  • H-Val-Arg-Arg-Phe-Pro-Trp-Trp-Trp-Pro-Phe-Leu-Arg-Arg-OH
  • H-VAL-ARG-ARG-PHE-PRO-TRP-TRP-TRP-PRO-PHE-LEU-ARG-ARG-OH
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  • Tritrpticin

    CAS:
    An anti-microbial peptide (AMP) of the cathelicidin family, originally discovered in pig neutrophils. Tritrpticin has potent and broad anti-microbial activity against Gram-positive and Gram-negative bacteria, some fungi, and protozoa.Tritrpticin is thought to exist in a range of conformations in solution, and recognise its targets with high selectivity and efficiency whilst displaying low haemolytic activity. The peptides three sequential tryptophan residues flanked by two prolines and four arginines are important for the peptides interaction with membranes and for its mechanism of action. The presence of these three tryptophan and four arginines residues, also class Tritrpticin as a member of the Arg/Trp-rich family of AMPs.
    Formula:C96H132N28O14
    Molecular weight:1,902.25 g/mol

    Ref: 3D-CRB1000021

    1mg
    282.00€
    500µg
    206.00€