CAS 179321-49-4

N-4-Boc-aminocyclohexanone

Description:

N-4-Boc-aminocyclohexanone is a chemical compound characterized by its structure, which includes a cyclohexanone ring and a tert-butyloxycarbonyl (Boc) protecting group attached to an amino group. This compound is typically used in organic synthesis, particularly in the preparation of various pharmaceuticals and biologically active molecules. The Boc group serves as a protective moiety for the amine, allowing for selective reactions without affecting the amino functionality. N-4-Boc-aminocyclohexanone is generally a solid at room temperature and is soluble in organic solvents such as dichloromethane and methanol. Its reactivity is influenced by the presence of the carbonyl group, which can participate in nucleophilic addition reactions. Additionally, the cyclohexanone framework contributes to the compound's conformational flexibility, which can be important in drug design and development. Safety data should be consulted for handling and storage, as with any chemical substance, to ensure proper safety measures are taken.

Formula: C₁₁H₁₉NO₃

InChI: InChI=1/C11H19NO3/c1-11(2,3)15-10(14)12-8-4-6-9(13)7-5-8/h8H,4-7H2,1-3H3,(H,12,14)

SMILES: CC(C)(C)OC(=NC1CCC(=O)CC1)O

Synonyms:

• Tert-Butyl 4-Oxocyclohexylcarbamate
• Boc-4-Aminocyclohexanone
• (4-Oxo-Cyclohexyl)-Carbamic Acidtert-Butylester
• 4-N-Boc-Aminocyclohexanone
• 4-N-Boc-4-Aminocyclohexanone
• 4-Aminocyclohexanonen-Bocprotected
• N-T-Boc-4-Aminocyclohexanone
• Tert-Butyl4-Oxocyclohexylcarbamate
• Carbamicacid,(4-Oxocyclohexyl)-,1,1-Dimethylethylester
• 4-(Boc-Amino)Cyclohexanone
• 4-(Tert-Butoxycarbonylamino)Cyclohexanone
• 4-N-Boc-Aminocyclohexanone4
• N-Boc-4-Aminocyclohexanone
• 4-(Tert-Butyloxycarbonylamino)Cyclohexanone
• Tert-Butyl 4-Oxocyclohexylacarbamate

4-(tert-Butoxycarbonylamino)cyclohexanone

CAS: 179321-49-4

Formula: C₁₁H₁₉NO₃

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 213.28

Ref: 3B-B3856

Carbamic acid, N-(4-oxocyclohexyl)-, 1,1-dimethylethyl ester

CAS: 179321-49-4

Formula: C₁₁H₁₉NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 213.2735

Ref: IN-DA0026XJ

4-Aminocyclohexan-1-one, N-BOC protected

CAS: 179321-49-4

4-Aminocyclohexan-1-one, N-BOC protected

Formula: C₁₁H₁₉NO₃

Purity: 98%

Color and Shape: white solid

Molecular weight: 213.27g/mol

Ref: 54-OR5501

N-4-Boc-Aminocyclohexanone

CAS: 179321-49-4

Formula: C₁₁H₁₉NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 213.277

Ref: 10-F011548

4-(N-Boc-amino)cyclohexanone

Controlled Product

CAS: 179321-49-4

Applications 4-(N-Boc-amino)cyclohexanone is an intermediate in the synthesis of tert-Butyl 1,7-diazaspiro[3.5]nonane-1-carboxylate (B692795). tert-Butyl 1,7-diazaspiro[3.5]nonane-1-carboxylate is a reagent in the preparation of -[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazin-3(2H)-ones as a potent poly(ADP-ribose) polymerase-1 inhibitors active in BRCA deficient cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ferrigno, F., et al.: Bioorg. Med. Chem. Lett., 20, 1100 (2010);

Formula: C₁₁H₁₉NO₃

Color and Shape: Neat

Molecular weight: 213.27

Ref: TR-B617675

4-N-Boc-aminocyclohexanone

CAS: 179321-49-4

4-N-Boc-aminocyclohexanone is a chemical that inhibits the proliferation of cancer cells in vitro. It also has an antiproliferative effect on fibroblast cells, which may be due to its ability to inhibit protein synthesis and induce cell death by apoptosis. 4-N-Boc-aminocyclohexanone can also be used for the preparation of photoresponsive polymers that are used in drug delivery systems. This compound can be prepared by reacting 4-aminocyclohexanol with formaldehyde in the presence of base. This reaction forms a five-membered ring via an amide bond. The amide group is then hydrolyzed to form the corresponding carboxylic acid. The colorimetric method is used to determine the degree of hydrolysis, which is determined by measuring the absorbance at 590 nm. In addition, this compound can be used as a reactive intermediate for other compounds like

Formula: C₁₁H₁₉NO₃

Purity: Min. 95%

Color and Shape: White To Light (Or Pale) Yellow Solid

Molecular weight: 213.27 g/mol

Ref: 3D-FB12555