CAS 179337-57-6

1-(4,5-Dihydro-2-thiazolyl)-3-azetidinethiol hydrochloride

Description:

1-(4,5-Dihydro-2-thiazolyl)-3-azetidinethiol hydrochloride is a chemical compound characterized by its unique structural features, which include a thiazole ring and an azetidine moiety. The thiazole ring contributes to its potential biological activity, often associated with various pharmacological properties. The azetidine ring, a four-membered saturated heterocycle, adds to the compound's structural complexity and may influence its reactivity and interaction with biological targets. As a hydrochloride salt, it is typically more soluble in water compared to its free base form, enhancing its bioavailability for pharmaceutical applications. The compound may exhibit properties such as antimicrobial or antifungal activity, making it of interest in medicinal chemistry. Its synthesis and characterization involve standard organic chemistry techniques, and it is important to handle it with care due to potential toxicity associated with thiol groups. Overall, this compound represents a class of heterocyclic compounds that are valuable in drug discovery and development.

Formula: C₆H₁₁ClN₂S₂

Synonyms:

• 2-(3-Mercaptoazetidin-1-yl)-2-thiazoline hydrochloride
• 3-Mercapto-1-(1,3-thiazolin-2-yl)azetidine hydrochloride
• 3-Azetidinethiol, 1-(4,5-dihydro-2-thiazolyl)-, monohydrochloride
• Tebipenam Side Chain
• Taibipeinan side chain

3-Azetidinethiol, 1-(4,5-dihydro-2-thiazolyl)-, hydrochloride (1:1)

CAS: 179337-57-6

Formula: C₆H₁₁ClN₂S₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 210.7479

Ref: IN-DA0026Y8

1-(4,5-Dihydrothiazol-2-Yl)Azetidine-3-Thiol Hydrochloride

CAS: 179337-57-6

1-(4,5-Dihydrothiazol-2-Yl)Azetidine-3-Thiol Hydrochloride

Purity: 98%

Molecular weight: 210.75g/mol

Ref: 54-OR1008936

1-(4,5-Dihydrothiazol-2-yl)azetidine-3-thiol hydrochloride

CAS: 179337-57-6

Formula: C₆H₁₁ClN₂S₂

Purity: 97%

Molecular weight: 210.74

Ref: 10-F224730

1-(4,5-Dihydro-2-thiazolyl)-3-azetidinethiol Hydrochloride

Controlled Product

CAS: 179337-57-6

Stability Hygroscopic
Applications 1-(4,5-Dihydro-2-thiazolyl)-3-azetidinethiol Hydrochloride is used as a reagent in the synthesis of Tebipenem Tetrahydrate (T012840); the active metabolite of Tebipenem Pivoxil (T012900) that shows excellent bactericidal activity against β-lactamase-nonproducing, ampicillin-resistant isolates.
References Nakashima, M. et al.: Nip. Kag. Ryo. Gak., 57, 90 (2009); Kishii, K. etal.: Antimicrob. Agents Chemother., 54, 3970 (2010); Xu, Z., et al.: Yaoxue Xuebao, 48, 993 (2013); Hazra, S., et al.: Biochem., 53, 3671 (2014); Li, H., et al.: Int. J. Antimicrob. Ag., 43, 92 (2014)

Formula: C₆H₁₁ClN₂S₂

Color and Shape: Neat

Molecular weight: 210.75

Ref: TR-D454190