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CAS 179479-04-0

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3'-O-Me-G(iBu)-2'-phosphoramidite

Description:
3'-O-Me-G(iBu)-2'-phosphoramidite, with the CAS number 179479-04-0, is a specialized chemical compound primarily used in the field of nucleic acid chemistry, particularly in the synthesis of oligonucleotides. This compound features a phosphoramidite functional group, which is crucial for the stepwise synthesis of DNA and RNA strands through solid-phase synthesis techniques. The "3'-O-Me" designation indicates that the molecule has a methoxy group at the 3' position of the ribose sugar, enhancing its stability and solubility. The "G(iBu)" portion refers to a guanine base modified with an isobutyl group, which can influence the compound's properties, such as its binding affinity and stability in biological systems. Overall, this phosphoramidite derivative is characterized by its ability to facilitate the incorporation of modified nucleotides into oligonucleotides, making it valuable for applications in molecular biology, genetic engineering, and therapeutic development. Its unique structural features contribute to its functionality in various biochemical processes.
Formula:C45H56N7O9P
Synonyms:
  • Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
  • 3’-O-Me-G(iBu)-2’-phosphoramidite
  • 5’-O-DMTr-N2-iso-butyroyl-3’-O-methyl guanosine-2’-CED-phosphoramidite
  • 3'-O-Me-G(iBu)-2'-phosphoramidite
  • 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-methyl-N-(2-methyl-1-oxopropyl)-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] Guanosine
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