CAS 179528-45-1

(2Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic acid

Description:

(2Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic acid, with the CAS number 179528-45-1, is an organic compound characterized by the presence of a propenoic acid backbone, a thiol group, and an iodine-substituted phenyl ring. This compound features a double bond configuration (Z) that influences its reactivity and stereochemistry. The presence of the mercapto (-SH) group imparts significant nucleophilicity, making it reactive in various chemical reactions, including those involving electrophiles. The iodine atom on the phenyl ring enhances the compound's potential for electrophilic substitution reactions and can also affect its biological activity. This compound may exhibit interesting properties such as antimicrobial or anticancer activities, which are common in thiol-containing compounds. Additionally, its solubility and stability can be influenced by the presence of the iodine substituent and the carboxylic acid functional group. Overall, (2Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic acid is a versatile compound with potential applications in medicinal chemistry and organic synthesis.

Formula: C₉H₇IO₂S

InChI: InChI=1S/C9H7IO2S/c10-7-3-1-6(2-4-7)5-8(13)9(11)12/h1-5,13H,(H,11,12)/b8-5-

InChI key: InChIKey=DJCVSFWGKYHMKH-YVMONPNESA-N

SMILES: C(=C(/C(O)=O)\S)\C1=CC=C(I)C=C1

PD150606

CAS: 179528-45-1

PD150606

Purity: ≥98%

Molecular weight: 306.12g/mol

Ref: 54-BUP21581

PD150606

CAS: 179528-45-1

PD150606 is a calpain inhibitor with neuroprotective activity that inhibits μ-calpains and interferes with excitotoxicity-dependent motor neuron death.

Formula: C₉H₇IO₂S

Purity: 98.19%

Color and Shape: Solid

Molecular weight: 306.12

Ref: TM-T3525

PD 150606

CAS: 179528-45-1

Formula: C₉H₇IO₂S

Molecular weight: 306.12

Ref: 7W-GK0334

PD 150606

Controlled Product

CAS: 179528-45-1

Applications PD 150606 is a novel mercaptoacrylate based compound and a potent inhibitor of Ca2+-dependent activation of calpain-1, a Ca2+-activated cytosolic cysteine protease. PD 150606 may potentially be developed as an anti-inflammatory agent. Neuroprotective product.
References Adams, S.E., et al.: Med. Chem. Comm., 3, 566 (2012); Ali, M.A., et al.: Biochem. Biophy. Res. Comm., 423, 1 (2012); Fujita, H., et al.: Arch. Biochem. Biophy., 516, 121 (2011);

Formula: C₉H₇IO₂S

Color and Shape: Neat

Molecular weight: 306.12

Ref: TR-P217485