CAS 179545-77-8

Tanomastat

Description:

Tanomastat is a synthetic compound that functions primarily as a matrix metalloproteinase (MMP) inhibitor, which plays a crucial role in the degradation of extracellular matrix components. This characteristic makes it of interest in the context of cancer research and treatment, as MMPs are often implicated in tumor invasion and metastasis. Tanomastat has been studied for its potential therapeutic applications, particularly in inhibiting tumor growth and spread by interfering with the tumor microenvironment. The compound is typically characterized by its specific molecular structure, which includes various functional groups that contribute to its biological activity. It is important to note that while Tanomastat has shown promise in preclinical studies, its clinical efficacy and safety profiles are subject to ongoing research and evaluation. As with many pharmaceutical compounds, understanding its pharmacokinetics, mechanism of action, and potential side effects is essential for its development and application in medical settings.

Formula: C₂₃H₁₉ClO₃S

InChI: InChI=1S/C23H19ClO3S/c24-20-12-10-17(11-13-20)16-6-8-18(9-7-16)22(25)14-19(23(26)27)15-28-21-4-2-1-3-5-21/h1-13,19H,14-15H2,(H,26,27)/t19-/m1/s1

InChI key: InChIKey=JXAGDPXECXQWBC-LJQANCHMSA-N

SMILES: C(C[C@H](CSC1=CC=CC=C1)C(O)=O)(=O)C2=CC=C(C=C2)C3=CC=C(Cl)C=C3

Synonyms:

• (2S)-4-(4'-chlorobiphenyl-4-yl)-4-oxo-2-[(phenylsulfanyl)methyl]butanoic acid
• (S)-4'-Chloro-g-oxo-a-[(phenylthio)methyl][1,1'-biphenyl]-4-butanoic acid
• (S)-4-[4-(4-Chlorophenyl)phenyl]-4-oxo-2-(phenylsulfanylmethyl)butanoic acid
• (αS)-4′-Chloro-γ-oxo-α-[(phenylthio)methyl][1,1′-biphenyl]-4-butanoic acid
• 4-(4'-Chlorobiphenyl-4-Yl)-4-Oxo-2-[(Phenylsulfanyl)Methyl]Butanoic Acid
• BAY12-9566,(S)-4Chloro-g-oxo-a-[(phenylthio)methyl][1,1biphenyl]-4-butanoicAcid
• Bay 12-9566
• Bay 129566
• [1,1′-Biphenyl]-4-butanoic acid, 4′-chloro-γ-oxo-α-[(phenylthio)methyl]-, (S)-
• [1,1′-Biphenyl]-4-butanoic acid, 4′-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-
• TANOMASTAT
• D03802
• (S)-4-(4'-Chloro-[1,1'-biphenyl]-4-yl)-4-oxo-2-((phenylthio)methyl)butanoic acid

[1,1'-Biphenyl]-4-butanoic acid, 4'-chloro-γ-oxo-α-[(phenylthio)methyl]-, (αS)-

CAS: 179545-77-8

Formula: C₂₃H₁₉ClO₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 410.9132

Ref: IN-DA00272W

Tanomastat

CAS: 179545-77-8

Formula: C₂₃H₁₉ClO₃S

Molecular weight: 410.91

Ref: 4Z-T-452001

Tanomastat

Controlled Product

CAS: 179545-77-8

Applications A Matrix Metalloproteinase inhibitor. An angiogenesis inhibitor.Optical Rotation +82° (C 1.5 acetone).

Formula: C₂₃H₁₉ClO₃S

Color and Shape: Neat

Molecular weight: 410.91

Ref: TR-T006900

Tanomastat

CAS: 179545-77-8

Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor.

Formula: C₂₃H₁₉ClO₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 410.91

Ref: TM-T16986