CAS 179688-52-9

6-Hydroxy-7-methoxy-4(3H)-quinazolinone

Description:

6-Hydroxy-7-methoxy-4(3H)-quinazolinone, with the CAS number 179688-52-9, is a chemical compound belonging to the quinazolinone class, which is characterized by a fused bicyclic structure containing a benzene ring and a pyrimidine ring. This compound typically exhibits properties such as being a solid at room temperature, with potential solubility in organic solvents. The presence of hydroxyl and methoxy functional groups contributes to its reactivity and potential biological activity, making it of interest in medicinal chemistry. Quinazolinones are often studied for their pharmacological properties, including anti-inflammatory, antimicrobial, and anticancer activities. The specific arrangement of substituents in 6-Hydroxy-7-methoxy-4(3H)-quinazolinone may influence its interaction with biological targets, enhancing its therapeutic potential. Additionally, the compound's stability, melting point, and spectral characteristics can be determined through various analytical techniques, including NMR and mass spectrometry, which are essential for confirming its identity and purity in research and development contexts.

Formula: C₉H₈N₂O₃

InChI: InChI=1S/C9H8N2O3/c1-14-8-3-6-5(2-7(8)12)9(13)11-4-10-6/h2-4,12H,1H3,(H,10,11,13)

InChI key: InChIKey=OKZIRNNFVQCDSA-UHFFFAOYSA-N

SMILES: O=C1C=2C(=CC(OC)=C(O)C2)NC=N1

Synonyms:

• 4(1H)-Quinazolinone, 6-hydroxy-7-methoxy-
• 4(3H)-Quinazolinone, 6-hydroxy-7-methoxy-
• 6-Hydroxy-7-Methoxyquinazoline-4-One
• 6-Hydroxy-7-methoxy-3H-quinazolin-4-one
• 6-Hydroxy-7-methoxy-4(3H)-quinazolinone
• 6-Hydydroxy-7-Methoxyquinazoline-4-One
• 6-hydroxy-7-methoxy-3,4-dihydroquinazolin-4(3H)-one
• 6-hydroxy-7-methoxyquinazolin-4(3H)-one
• 7-Methoxyquinazoline-4,6-Diol
• 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one

4(3H)-Quinazolinone, 6-hydroxy-7-methoxy-

CAS: 179688-52-9

Formula: C₉H₈N₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 192.1714

Ref: IN-DA00276Y

6-Hydroxy-7-methoxy-1H-quinazolin-4-one

CAS: 179688-52-9

6-Hydroxy-7-methoxy-1H-quinazolin-4-one

Purity: 98%

Molecular weight: 192.17g/mol

Ref: 54-OR941735

6-Hydroxy-7-methoxy-3H-quinazolin-4-one

CAS: 179688-52-9

Formula: C₉H₈N₂O₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 192.17

Ref: 3B-H1606

6-Hydroxy-7-methoxy-4(1H)-quinazolinone

CAS: 179688-52-9

Color and Shape: Neat

Ref: 86-MM3563.23

Gefitinib Impurity 4

CAS: 179688-52-9

Formula: C₉H₈N₂O₃

Molecular weight: 192.18

Ref: 4Z-G-2327

6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one

CAS: 179688-52-9

6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one is an amination of chloropropane and morpholinyl with 3-chloro-4-fluoroaniline. It cyclizes to form a quinazolinone. This compound was synthesized in order to produce a cytotoxic agent for cancer treatment.

Formula: C₉H₈N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 192.17 g/mol

Ref: 3D-FH41698

6-hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one

CAS: 179688-52-9

Purity: 98%

Molecular weight: 192.174

Ref: 10-F960163

6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one

CAS: 179688-52-9

Formula: C₉H₈N₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 192.174

Ref: 10-F079757

6-Hydroxy-7-methoxy-4(1H)-quinazolinone

Controlled Product

CAS: 179688-52-9

Applications 6-Hydroxy-7-methoxy-4(1H)-quinazolinone is a reactant used in the preparation of 4-anilinoquinazoline derivatives that have shown antitumor activities. 6-Hydroxy-7-methoxy-4(1H)-quinazolinone was also used as a reactant in the synthetic preparation of 2-arylbenzothiazoles as kinase inhibitors.
References Chandregowda, V., et al.: Eur. J. Med. Chem., 44, 3046 (2009); Tasler, S., et al.: Bioorg. Med. Chem. Lett., 17, 6728 (2009);

Formula: C₉H₈N₂O₃

Color and Shape: Beige

Molecular weight: 192.17

Ref: TR-H947105

Gefitinib Impurity 4

CAS: 179688-52-9

Formula: C₉H₈N₂O₃

Molecular weight: 192.17

Ref: ST-EA-CP-G14020