CAS 1797099-76-3

N,N’-Desethylene-N-Desmethyl Levofloxacin Hydrochloride Hydrochloride

CAS: 1797099-76-3

Applications N,N-Didesethylene Levofloxacin is an impurity of Levofloxacin (L360000), the S-(-)-enantiomer of Ofloxacin (O245750). Levofloxacin is an antibacterial agent used against gram-negative organisms.
References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992), North, D.S., et al.: Pharmacotherapy, 18, 915 (1998), Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003),

Formula: C₁₅H₁₆FN₃O₄·ClH

Color and Shape: Yellow

Molecular weight: 357.7646

Ref: TR-D289340

Levofloxacin diamine impurity

CAS: 1797099-76-3

Levofloxacin is a synthetic fluoroquinolone antibiotic. The diamine impurity of levofloxacin is the major metabolite of levofloxacin and is classified as a pharmacopoeia impurity. Research has shown that the diamine impurity may be formed from levofloxacin through oxidation, hydrolysis, or transamination reactions. Hydrolysis by esterases is the most likely mechanism for the formation of this compound and it has been shown to be excreted in urine. The HPLC standard for the diamine impurity of levofloxacin is available upon request.

Purity: Min. 95%

Ref: 3D-FL176031