CAS 1797985-81-9

N-Trityl Candesartan Ethyl Ester

Description:

N-Trityl Candesartan Ethyl Ester is a chemical compound that belongs to the class of angiotensin II receptor antagonists, specifically designed for the treatment of hypertension and heart failure. It is a derivative of candesartan, which is known for its efficacy in blocking the effects of angiotensin II, a peptide that causes blood vessels to constrict. The "N-Trityl" modification enhances its lipophilicity and may improve its pharmacokinetic properties. This compound typically exhibits characteristics such as a high molecular weight, specific solubility in organic solvents, and stability under standard laboratory conditions. Its structure includes a trityl group, which contributes to its unique properties, and an ethyl ester moiety that can influence its bioavailability. As with many pharmaceutical compounds, the synthesis and characterization of N-Trityl Candesartan Ethyl Ester involve various analytical techniques, including NMR, mass spectrometry, and HPLC, to ensure purity and confirm its chemical identity. Safety and handling precautions are essential, as with any chemical substance, due to potential biological activity and toxicity.

Formula: C₄₅H₃₈N₆O₃

Synonyms:

• 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-, ethyl ester

Candesartan Cilexetil Impurity 15

CAS: 1797985-81-9

Formula: C₄₅H₃₈N₆O₃

Color and Shape: White To Off-White Solid

Molecular weight: 710.84

Ref: 4Z-C-0131

N-Trityl Candesartan Ethyl Ester

Controlled Product

CAS: 1797985-81-9

Applications Candesartan analog as angiotensin II antagonist.
References Bakshi, M., et al.: J. Pharm. Biomed. Anal., 28, 1011 (2002),

Formula: C₄₅H₃₈N₆O₃

Color and Shape: Neat

Molecular weight: 710.82

Ref: TR-T887210

N-Trityl candesartan ethyl ester

CAS: 1797985-81-9

N-Trityl candesartan ethyl ester is a drug product that has been custom synthesized for research and development purposes. It is an impurity standard for the synthesis of metoprolol. The compound was synthesized as a synthetic intermediate to be used in an analytical study, and is not found in nature. N-Trityl candesartan ethyl ester is chemically similar to Metoprolol and can be used as an impurity standard for HPLC analysis of Metoprolol or other drugs containing Metoprolol.

Formula: C₄₅H₃₈N₆O₃

Purity: Min. 95%

Molecular weight: 710.80 g/mol

Ref: 3D-XWC98581

Candesartan Ethyl Ester N2-Trityl Analog

CAS: 1797985-81-9

Formula: C₄₅H₃₈N₆O₃

Molecular weight: 710.84

Ref: ST-EA-CP-C50033