CAS 17990-42-0
:3-Oxo-olean-12-en-28-oic acid
Description:
3-Oxo-olean-12-en-28-oic acid, also known by its CAS number 17990-42-0, is a triterpenoid compound derived from the oleanane family of natural products. This substance is characterized by its pentacyclic structure, which includes a ketone functional group at the C-3 position and a carboxylic acid group at the C-28 position. It typically exhibits a white to off-white crystalline appearance. The compound is known for its potential biological activities, including anti-inflammatory, antioxidant, and anticancer properties, making it of interest in pharmacological research. Its solubility is generally low in water but may be more soluble in organic solvents. The presence of the oleanane skeleton contributes to its stability and reactivity, influencing its interactions in biological systems. As a natural product, it can be isolated from various plant sources, particularly those in traditional medicine, and is often studied for its therapeutic potential.
Formula:C30H46O3
InChI:InChI=1/C30H46O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-22H,9-18H2,1-7H3,(H,32,33)/t20-,21-,22+,27-,28+,29+,30-/m0/s1
Synonyms:- Oleanonic acid
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Found 10 products.
Olean-12-en-28-oic acid, 3-oxo-
CAS:Formula:C30H46O3Purity:98%Color and Shape:SolidMolecular weight:454.6844Oleanonic acid
CAS:Formula:C30H46O3Purity:≥ 95.0%Color and Shape:White to off-white powder or solidMolecular weight:454.70Oleanonic acid
CAS:3-oxo-Olean-12-en-28-oic acid and kulinone have cytotoxic effects, with IC50 values of 5.6-21.2 μg/mL.Formula:C30H46O3Purity:95%~99%Molecular weight:454.695Oleanonic Acid
CAS:Formula:C30H46O3Purity:>95.0%(T)(HPLC)Color and Shape:White to Light yellow to Green powder to crystalMolecular weight:454.70Oleanonic acid
CAS:Oleanonic acid (3-Ketooleanolic Acid) is relatively non-toxic, hepatoprotective, and exhibits antitumor and andantiviral properties.Formula:C30H46O3Purity:98.35% - 99.22%Color and Shape:SolidMolecular weight:454.68Oleanonic acid
CAS:Carboxylic acid with ketone functionFormula:C30H46O3Purity:≥ 90.0 % (HPLC)Molecular weight:454.68Oleanonic acid
CAS:Controlled Product<p>Oleanonic acid is a natural product that belongs to the group of compounds called dehydrocostus lactones. It has been shown to induce apoptosis in leukemia cells, with an IC 50 of 0.1 μM. Oleanonic acid also inhibits cancer cell growth in vitro and induces apoptosis in human serum-derived K562 cells. It activates caspase-3 and caspase-8, leading to the cleavage of PARP and DNA fragmentation. Oleanonic acid also has anti-inflammatory properties, inhibiting PGE2 production by blocking cyclooxygenase activity. The mechanism of action for these effects is not yet known but may be due to its ability to inhibit mitochondrial functions.br>br><br>br><br>The structure of oleanonic acid has been elucidated by 1H NMR spectroscopy and mass spectrometry.<br>Oleanonic acid can be purified from the bark of the "Zelkova serrata</p>Formula:C30H46O3Purity:Min. 95%Color and Shape:PowderMolecular weight:454.68 g/mol
