CAS 1799631-75-6

MIK665

Description:

MIK665, identified by its CAS number 1799631-75-6, is a chemical compound that belongs to a class of molecules known as small-molecule inhibitors. It has garnered attention in the field of medicinal chemistry, particularly for its potential applications in oncology. MIK665 functions primarily as a selective inhibitor of certain proteins involved in the regulation of apoptosis, specifically targeting the BCL-2 family of proteins. This mechanism of action is significant as it can promote cancer cell death, making it a candidate for therapeutic strategies against various malignancies. The compound is characterized by its specific binding affinity, which allows it to disrupt the survival signals in cancer cells. Additionally, MIK665 has been studied for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion (ADME), which are crucial for determining its efficacy and safety profile in clinical settings. Ongoing research continues to explore its potential in combination therapies and its effectiveness across different cancer types.

Formula: C₄₇H₄₄ClFN₆O₆S

Synonyms:

• S64315 (MIK665)
• S64315
• MIK665 (S-64315, MIK-665)
• MIK665
• Benzenepropanoic acid, α-[[(5S)-5-[3-chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[2-(2-methoxyphenyl)-4-pyrimidinyl]methoxy]-, (αR)-
• (2S)-2-(5-(3-chloro-2-methyl-4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yloxy)-3-(2-((2-(2-methoxyphenyl)pyrimidin-4-yl)methoxy)phenyl)propanoic acid
• MIK665,S64315

Benzenepropanoic acid, α-[[(5S)-5-[3-chloro-2-methyl-4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy]-2-[[2-(2-methoxyphenyl)-4-pyrimidinyl]methoxy]-, (αR)-

CAS: 1799631-75-6

Formula: C₄₇H₄₄ClFN₆O₆S

Purity: 99%

Color and Shape: Solid

Molecular weight: 875.4053

Ref: IN-DA01V4YY

MIK665

CAS: 1799631-75-6

MIK665

Purity: ≥98%

Molecular weight: 875.41g/mol

Ref: 54-BUP09077

MIK665

CAS: 1799631-75-6

MIK665 (S-64315) (S-64315) has an inhibitory effect on myeloid leukemia.

Formula: C₄₇H₄₄ClFN₆O₆S

Purity: 95.47% - 99.28%

Color and Shape: Solid

Molecular weight: 875.41

Ref: TM-T12629L

MIK665

CAS: 1799631-75-6

MIK665 is a humanized monoclonal antibody that is used for the diagnosis of cancer. It binds to a hydroxyl group on the surface of cells, which are typically overexpressed in tumor cells. MIK665 can also induce apoptosis in primary cells, such as human immunoglobulin G (IgG) and IgM-producing B lymphocytes and T lymphocytes. The antibody has been shown to activate pro-apoptotic proteins by triggering the release of cytochrome C from mitochondria. This process leads to the activation of caspases, which are enzymes that break down protein structures within cells and lead to cell death. MIK665 has been shown to inhibit viral replication through its ability to neutralize fatty acids on the surface of viruses. Its use has also been shown to be synergistic with other drugs when used in combination with chemotherapeutic agents in metastatic colorectal cancer patients.

Purity: Min. 95%

Ref: 3D-BM170717