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CAS 1799667-33-6

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α-Amylase-IN-12

Description:
α-Amylase-IN-12, with the CAS number 1799667-33-6, is a chemical compound that serves as an inhibitor of the enzyme α-amylase, which plays a crucial role in carbohydrate metabolism by catalyzing the hydrolysis of starch into sugars. This compound is characterized by its ability to selectively bind to the active site of α-amylase, thereby preventing the enzyme from functioning effectively. As a result, α-Amylase-IN-12 can be utilized in various applications, including research on metabolic disorders, diabetes management, and the development of weight management products. The compound's structure typically includes functional groups that enhance its binding affinity and specificity for α-amylase. Additionally, its pharmacokinetic properties, such as solubility and stability, are essential for its effectiveness in biological systems. Overall, α-Amylase-IN-12 represents a valuable tool in biochemical research and therapeutic applications targeting carbohydrate digestion and metabolism.
Synonyms:
  • 5(4H)-Oxazolone, 4-[(3,4-dihydroxyphenyl)methylene]-2-phenyl-, (4Z)-
  • α-Amylase-IN-12
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  • α-Amylase-IN-12

    CAS:
    <p>α-Amylase-IN-12 (Compound 5e) is an α-amylase inhibitor with an IC50 of 0.15 mM, functioning through a mixed inhibition mode. It exhibits an IC50 of 9.40 mM against α-glucosidase. This compound enhances glucose uptake in yeast cells and demonstrates significant anti-glycation activity at high concentrations. α-Amylase-IN-12 is applicable for diabetes research.</p>
    Formula:C16H11NO4
    Color and Shape:Solid
    Molecular weight:281.263