CAS 1799706-65-2

MMAF sodium

CAS: 1799706-65-2

MMAF sodium is a highly specialized payload used in the development of antibody-drug conjugates (ADCs). It is derived from the synthetic modification of the cytotoxic agent monomethyl auristatin F, which itself originates from dolastatin 10, a compound produced by marine organisms. The mechanism of action of MMAF sodium involves the inhibition of tubulin polymerization. This disruption of the microtubule network effectively halts cell division, leading to apoptosis in rapidly dividing cancer cells.

Formula: C₃₉H₆₄N₅NaO₈

Purity: Min. 95%

Molecular weight: 753.9 g/mol

Ref: 3D-ZWC70665

MMAF sodium

CAS: 1799706-65-2

MMAF sodium, a potent tubulin inhibitor in ADCs like Vorsetuzumab mafodotin and SGN-CD19A, acts as an antitumor agent.

Formula: C₃₉H₆₄N₅NaO₈

Purity: 98%

Color and Shape: Solid

Molecular weight: 753.94

Ref: TM-T16122