CAS 1799711-22-0

(1R)-3-(3,4-Dimethoxyphenyl)-1-[3-[[4-[[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]amino]-1,4-dioxobutyl]amino]phenyl]propyl (2S)-1-(3,3-dimethyl-1,2-dioxopentyl)-2-piperidinecarboxylate

Description:

The chemical substance with the name "(1R)-3-(3,4-Dimethoxyphenyl)-1-[3-[[4-[[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]amino]-1,4-dioxobutyl]amino]phenyl]propyl (2S)-1-(3,3-dimethyl-1,2-dioxopentyl)-2-piperidinecarboxylate" and CAS number "1799711-22-0" is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as amides, esters, and dioxo moieties. This compound likely exhibits significant biological activity due to its structural features, which may interact with various biological targets. The presence of piperidine and isoindole rings suggests potential pharmacological properties, possibly in the realm of medicinal chemistry. Additionally, the dimethoxyphenyl and dioxopentyl groups may influence its solubility and bioavailability. As a synthetic compound, it may be of interest in drug development, particularly for conditions that require modulation of specific biological pathways. However, detailed studies on its pharmacodynamics, pharmacokinetics, and toxicity would be essential to fully understand its potential applications.

Formula: C₅₃H₆₄N₆O₁₄

InChI: InChI=1S/C53H64N6O14/c1-6-53(2,3)47(64)51(68)58-28-10-7-16-37(58)52(69)73-38(21-18-32-19-22-39(70-4)41(29-32)71-5)33-13-11-14-34(30-33)56-43(61)25-24-42(60)54-26-8-9-27-55-45(63)31-72-40-17-12-15-35-46(40)50(67)59(49(35)66)36-20-23-44(62)57-48(36)65/h11-15,17,19,22,29-30,36-38H,6-10,16,18,20-21,23-28,31H2,1-5H3,(H,54,60)(H,55,63)(H,56,61)(H,57,62,65)/t36?,37-,38+/m0/s1

InChI key: InChIKey=RIBCWKRMNKOGRN-GGJINPDOSA-N

SMILES: O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCNC(CCC(NC4=CC([C@H](OC(=O)[C@H]5N(C(C(C(CC)(C)C)=O)=O)CCCC5)CCC6=CC(OC)=C(OC)C=C6)=CC=C4)=O)=O)=O

Synonyms:

• (1R)-3-(3,4-Dimethoxyphenyl)-1-[3-[[4-[[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]amino]-1,4-dioxobutyl]amino]phenyl]propyl (2S)-1-(3,3-dimethyl-1,2-dioxopentyl)-2-piperidinecarboxylate
• 2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-3-(3,4-dimethoxyphenyl)-1-[3-[[4-[[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]amino]-1,4-dioxobutyl]amino]phenyl]propyl ester, (2S)-
• dFKBP-1

dFKBP-1

CAS: 1799711-22-0

dFKBP-1 is a potent and PROTAC-based FKBP12 degrader. dFKBP-1 incorporates the ligand SLF of FKBP12, the Thalidomide based cereblon ligand and a linker[1].

Formula: C₅₃H₆₄N₆O₁₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 1009.11

Ref: TM-T18597

dFKBP-1

CAS: 1799711-22-0

dFKBP-1 is a heat shock protein derived from Drosophila melanogaster, which is commonly used as a model organism in genetic and molecular biology research. This protein, known as Drosophila FK506-binding protein 1 (dFKBP-1), originates from Drosophila and is involved in essential cellular processes.

Formula: C₅₃H₆₄N₆O₁₄

Purity: Min. 95%

Molecular weight: 1,009.1 g/mol

Ref: 3D-ZWC71122