CAS 179985-52-5

1-ACETAMIDO-4-CYANO-3-METHYLISOQUINOLINE

Description:

1-Acetamido-4-cyano-3-methylisoquinoline is a chemical compound characterized by its isoquinoline structure, which is a bicyclic aromatic compound. This substance features an acetamido group (-NHCOCH3) and a cyano group (-CN) attached to the isoquinoline framework, contributing to its unique reactivity and potential applications in medicinal chemistry. The presence of the methyl group at the 3-position enhances its lipophilicity, which can influence its biological activity and solubility. The cyano group can participate in various chemical reactions, making this compound a versatile intermediate in organic synthesis. Additionally, the acetamido group may enhance the compound's ability to form hydrogen bonds, potentially affecting its interactions with biological targets. Overall, 1-acetamido-4-cyano-3-methylisoquinoline is of interest for its potential pharmacological properties and as a building block in the synthesis of more complex molecules. Its specific applications and biological activities would depend on further research and exploration within the field of medicinal chemistry.

Formula: C₁₃H₁₁N₃O

InChI: InChI=1/C13H11N3O/c1-8-12(7-14)10-5-3-4-6-11(10)13(15-8)16-9(2)17/h3-6H,1-2H3,(H,15,16,17)

SMILES: Cc1c(C#N)c2ccccc2c(n1)N=C(C)O

Synonyms:

• 1-Acetamido-3-Methyl-4-Cyanoisoquinoline
• 1-Acetamido-3-Methyl-4-Cyanosoquinoline
• 1-Acetamido-3-methyl-4-cyanosoqinoline
• N-(4-cyano-3-methylisoquinolin-1-yl)acetamide

Acetamide, N-(4-cyano-3-methyl-1-isoquinolinyl)-

CAS: 179985-52-5

Formula: C₁₃H₁₁N₃O

Purity: 97%

Color and Shape: Solid

Molecular weight: 225.2459

Ref: IN-DA0021JI

PKA-IN-1

CAS: 179985-52-5

PKA-IN-1

Purity: ≥95%

Molecular weight: 225.25g/mol

Ref: 54-BUP06866

PKA-IN-1

CAS: 179985-52-5

PKA-IN-1 is a selective and potent cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor (IC50: 0.03 μM).PKA-IN-1 can be used to study

Formula: C₁₃H₁₁N₃O

Purity: 97.52%

Color and Shape: Solid

Molecular weight: 225.25

Ref: TM-T39217

1-Acetamido-4-cyano-3-methylisoquinoline

Controlled Product

CAS: 179985-52-5

Applications A selective inhibitor of cyclic AMP-dependent protein kinase (PKA).
References Lu, X.Z., Biol. Chem. Hoppe-Seyler, 377, 373 (1996)

Formula: C₁₃H₁₁N₃O

Color and Shape: Neat

Molecular weight: 225.25

Ref: TR-A150525