CAS 179986-95-9

(Leu31,Pro34)-Peptide YY (human)

Description:

(Leu31,Pro34)-Peptide YY (human), with the CAS number 179986-95-9, is a peptide that plays a significant role in regulating appetite and gastrointestinal functions. It is a modified form of the naturally occurring peptide YY (PYY), which is secreted by the L-cells in the intestines in response to food intake. This peptide consists of 36 amino acids and is characterized by its ability to inhibit gastric motility and stimulate the absorption of nutrients. The specific substitutions of leucine at position 31 and proline at position 34 enhance its biological activity and stability compared to the native form. (Leu31,Pro34)-PYY interacts with neuropeptide Y receptors, particularly Y2 receptors, influencing satiety signals and energy homeostasis. Its therapeutic potential is being explored in the context of obesity and metabolic disorders, making it a subject of interest in both pharmacology and nutritional science. Overall, this peptide exemplifies the intricate relationship between gut hormones and appetite regulation.

Synonyms:

• H-Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Leu-Thr-Arg-Pro-Arg-Tyr-NH2

(Leu31,Pro34)-Peptide YY (human) trifluoroacetate salt

CAS: 179986-95-9

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Formula: C₁₉₅H₂₉₆N₅₄O₅₆

Purity: Min. 95%

Molecular weight: 4,292.77 g/mol

Ref: 3D-FL108785