CAS 180083-23-2
:SB 224289
Description:
SB 224289, with the CAS number 180083-23-2, is a chemical compound that has been studied primarily for its role as a selective inhibitor of certain protein kinases, particularly those involved in signaling pathways related to cell proliferation and survival. This compound is characterized by its ability to modulate biological processes, making it of interest in pharmacological research, particularly in the context of cancer therapy and other diseases where aberrant kinase activity is a factor. SB 224289 exhibits a specific binding affinity for its target kinases, which allows for the potential development of targeted therapies with reduced side effects compared to non-selective inhibitors. Its chemical structure includes functional groups that contribute to its biological activity and solubility properties, influencing its pharmacokinetics and bioavailability. As with many research compounds, further studies are necessary to fully elucidate its mechanism of action, therapeutic potential, and safety profile in clinical applications.
Formula:C32H32N4O3
InChI:InChI=1S/C32H32N4O3/c1-20-16-25(30-33-21(2)39-34-30)8-9-26(20)22-4-6-23(7-5-22)31(37)36-13-10-24-17-29-27(18-28(24)36)32(19-38-29)11-14-35(3)15-12-32/h4-9,16-18H,10-15,19H2,1-3H3
InChI key:InChIKey=ATQMRMGXINTJHV-UHFFFAOYSA-N
SMILES:C(=O)(N1C=2C=C3C4(COC3=CC2CC1)CCN(C)CC4)C5=CC=C(C=C5)C6=C(C)C=C(C=C6)C=7N=C(C)ON7
Synonyms:- (2′-Methyl-4′-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1′-biphenyl]-4-yl)(1′-methyl-6,7-dihydrospiro[furo[2,3-f]indole-3,4′-piperidin]-5(2H)-yl)methanone
- 1Methyl-5-((2methyl-4(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl)carbonyl)-2,3,6,7-tetrahydrospiro(furo[2.3-f]ind
- 6,7-Dihydro-1'-Methyl-5-[[2'-Methyl-4'-(5-Methyl-1,2,4-Oxadiazol-3-Yl)[1,1'-Biphenyl]-4-Yl]Carbonyl]-Spiro[2H-Furo[2,3-F]Indole-3(5H) Hydrochloride
- Methanone, [2′-methyl-4′-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl](2,5,6,7-tetrahydro-1′-methylspiro[3H-furo[2,3-f]indole-3,4′-piperidin]-5-yl)-
- SB224289HCl
- Sb 224,289 Hydrochloride
- Sb 224289
- Spiro[2H-furo[2,3-f]indole-3(5H),4′-piperidine], 6,7-dihydro-1′-methyl-5-[[2′-methyl-4′-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl]carbonyl]-
- [2′-Methyl-4′-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1′-biphenyl]-4-yl](2,5,6,7-tetrahydro-1′-methylspiro[3H-furo[2,3-f]indole-3,4′-piperidin]-5-yl)methanone
- [4-[2-Methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]phenyl]-(1′-methylspiro[6,7-dihydro-2H-furo[2,3-f]indole-3,4′-piperidine]-5-yl)methanone
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