CAS 1801344-14-8

N-[5-[(3R)-3-Hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide

Description:

N-[5-[(3R)-3-Hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide, with CAS number 1801344-14-8, is a complex organic compound characterized by its multi-cyclic structure and the presence of various functional groups. This substance features an oxazole ring, which contributes to its heterocyclic nature, and includes a pyridine moiety that enhances its potential biological activity. The presence of a hydroxyl group on the pyrrolidine ring suggests potential for hydrogen bonding, which may influence its solubility and interaction with biological targets. Additionally, the morpholine group may provide flexibility and steric effects that can affect the compound's pharmacokinetics and pharmacodynamics. Overall, this compound is likely to exhibit specific interactions with biological systems, making it of interest in medicinal chemistry and drug development, particularly in the context of targeting certain receptors or enzymes. Its detailed characteristics, including solubility, stability, and reactivity, would require further empirical investigation.

Formula: C₂₄H₂₅N₇O₅

InChI: InChI=1S/C24H25N7O5/c1-14-10-15(2-4-25-14)23-27-18(13-35-23)22(33)26-17-11-19-20(28-21(17)31-5-3-16(32)12-31)29-24(36-19)30-6-8-34-9-7-30/h2,4,10-11,13,16,32H,3,5-9,12H2,1H3,(H,26,33)/t16-/m1/s1

InChI key: InChIKey=SJHNWSAWWOAWJH-MRXNPFEDSA-N

SMILES: N(C(=O)C=1N=C(OC1)C=2C=C(C)N=CC2)C3=C(N=C4C(=C3)OC(=N4)N5CCOCC5)N6CC[C@@H](O)C6

Synonyms:

• 4-Oxazolecarboxamide, N-[5-[(3R)-3-hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-
• Emavusertib
• (R)-N-{5-(3-Hydroxypyrrolidin-1-yl)-2-morpholinooxazolo[4,5-b]pyridin-6-yl}-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide
• CA 4948
• N-[5-[(3R)-3-Hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide
• Emavusertib(CA-4948)
• rheumatoid,inflammation,CD135,inhibit,IL-1R associated kinase,CA4948,lymphoma,Interleukin-1 receptor associated kinase,Fms like tyrosine kinase 3,FLT3,arthritis,Inhibitor,CA 4948,Cluster of differentiation antigen 135,Myd88,IL-1R,IRAK,Toll,CA-4948

4-Oxazolecarboxamide, N-[5-[(3R)-3-hydroxy-1-pyrrolidinyl]-2-(4-morpholinyl)oxazolo[4,5-b]pyridin-6-yl]-2-(2-methyl-4-pyridinyl)-

CAS: 1801344-14-8

Formula: C₂₄H₂₅N₇O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 491.4992

Ref: IN-DA01PXXD

CA-4948

CAS: 1801344-14-8

CA-4948

Purity: ≥98%

Molecular weight: 491.5g/mol

Ref: 54-BUP03805

CA-4948

CAS: 1801344-14-8

CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.

Formula: C₂₄H₂₅N₇O₅

Purity: 99.35% - 99.88%

Color and Shape: Solid

Molecular weight: 491.5

Ref: TM-T9027

Ca-4948

CAS: 1801344-14-8

CA-4948 is a potent small molecule inhibitor, specifically targeting interleukin-1 receptor-associated kinase 4 (IRAK4), which plays a critical role in the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling pathways. This compound originates from targeted drug discovery efforts aimed at modulating immune-mediated pathways crucial for inflammatory responses.

Formula: C₂₄H₂₅N₇O₅

Purity: Min. 95%

Molecular weight: 491.5 g/mol

Ref: 3D-BXC34414