CAS 1801787-56-3

Formula: C29H32F3N5O3

InChI: InChI=1S/C29H32F3N5O3/c1-35-7-9-37(10-8-35)26-6-5-22(21-4-2-3-20(15-21)19-36-11-13-40-14-12-36)16-25(26)34-28(39)23-18-33-27(38)17-24(23)29(30,31)32/h2-6,15-18H,7-14,19H2,1H3,(H,33,38)(H,34,39)

InChI key: DJOVLOYCGXNVPI-UHFFFAOYSA-N

SMILES: CN1CCN(CC1)C2=C(C=C(C=C2)C3=CC=CC(=C3)CN4CCOCC4)NC(=O)C5=CNC(=O)C=C5C(F)(F)F

3-Pyridinecarboxamide, 1,6-dihydro-N-[4-(4-methyl-1-piperazinyl)-3'-(4-morpholinylmethyl)[1,1'-biphenyl]-3-yl]-6-oxo-4-(trifluoromethyl)-

CAS: 1801787-56-3

Formula: C₂₉H₃₂F₃N₅O₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 555.5913

Ref: IN-DA0021QY

OICR-9429

CAS: 1801787-56-3

OICR-9429

Formula: C₂₉H₃₂F₃N₅O₃

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 555.59

Ref: 54-BUP03024

6-Oxo-4-Trifluoromethyl-1,6-Dihydro-Pyridine-3-Carboxylic Acid [4-(4-Methyl-Piperazin-1-Yl)-3'-Morpholin-4-Ylmethyl-Biphenyl-3-Yl]-Amide

CAS: 1801787-56-3

6-Oxo-4-Trifluoromethyl-1,6-Dihydro-Pyridine-3-Carboxylic Acid [4-(4-Methyl-Piperazin-1-Yl)-3'-Morpholin-4-Ylmethyl-Biphenyl-3-Yl]-Amide

Formula: C₂₉H₃₂F₃N₅O₃

Purity: 99%

Molecular weight: 555.59

Ref: 54-PC108771

OICR-9429

CAS: 1801787-56-3

OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.

Formula: C₂₉H₃₂F₃N₅O₃

Purity: 97.07% - 99.93%

Color and Shape: Yellow Solid

Molecular weight: 555.59

Ref: TM-T6916

N-[4-(4-methylpiperazin-1-yl)-3′-[(morpholin-4-yl)methyl]-[1,1′-biphenyl]-3-yl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide

CAS: 1801787-56-3

Purity: 99%

Molecular weight: 555.6019897

Ref: 10-F811831

OICR 9429

CAS: 1801787-56-3

A highly selective WD repeat-containing protein 5 (Wdr5) antagonist and modulator of histone lysine methylation. The compound competitively disrupts the interaction between the Wdr5 and Wdr5-INteracting region (WIN) of methyltransferases. It inhibits the cell proliferation and restores differentiation in p30-dependent acute myeloid leukemia models.

Formula: C₂₉H₃₂F₃N₅O₃

Purity: Min. 95%

Molecular weight: 555.59 g/mol

Ref: 3D-BO163662