CAS 1801863-88-6
:(4E)-TCO-PEG4-DBCO
Description:
(4E)-TCO-PEG4-DBCO, with the CAS number 1801863-88-6, is a chemical compound that belongs to the class of bioorthogonal reagents, specifically designed for use in click chemistry applications. This compound features a trans-cyclooctene (TCO) moiety, which is known for its rapid and selective reaction with dibenzocyclooctyne (DBCO) derivatives, facilitating efficient labeling and conjugation processes in biological systems. The PEG4 (polyethylene glycol) segment enhances the solubility and biocompatibility of the compound, making it suitable for various applications in bioconjugation, drug delivery, and imaging. The presence of the DBCO group allows for strain-promoted azide-alkyne cycloaddition (SPAAC), a reaction that occurs under mild conditions and is particularly useful in live-cell imaging and targeting. Overall, (4E)-TCO-PEG4-DBCO is characterized by its stability, ease of use, and effectiveness in facilitating specific interactions in complex biological environments, making it a valuable tool in chemical biology and medicinal chemistry research.
Formula:C38H49N3O8
Synonyms:- (4E)-TCO-PEG4-DBCO
- TCO-PEG4-DBCO
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Found 4 products.
TCO-PEG4-DBCO
CAS:<p>TCO-PEG4-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].</p>Formula:C38H49N3O8Purity:98%Color and Shape:SolidMolecular weight:675.823TCO-PEG4-DBCO
CAS:<p>TCO-PEG4-DBCO is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. TCO-PEG4-DBCO is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>Formula:C38H49N3O8Purity:Min. 95%Molecular weight:675.8 g/mol
