CAS 1801881-15-1

2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro-

Description:

2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro- is a chemical compound characterized by its pyridinone core structure, which features a nitrogen-containing heterocyclic ring. The presence of a 4-aminophenyl group indicates that there is an amino group attached to a phenyl ring, contributing to its potential biological activity. The chloro substituent at the 3-position of the pyridinone ring suggests that this compound may exhibit unique reactivity and properties, such as altered solubility and interaction with biological targets. This compound may be of interest in medicinal chemistry due to its structural features, which could influence its pharmacological properties. Additionally, the dihydro configuration implies that the compound may exist in a reduced form, affecting its stability and reactivity. Overall, this compound's characteristics, including its molecular structure and substituents, suggest potential applications in drug development or as a research tool in various chemical and biological studies.

Formula: C₁₁H₁₁ClN₂O

Synonyms:

• 2(1H)-Pyridinone, 1-(4-aminophenyl)-3-chloro-5,6-dihydro-
• 1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone
• Apixaban Impurity 101

Apixaban Impurity 110

CAS: 1801881-15-1

Formula: C₁₁H₁₁ClN₂O

Molecular weight: 222.67

Ref: 4Z-A-102122

1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone

Controlled Product

CAS: 1801881-15-1

Applications 1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone is an impurity of Apixaban (A726700(P)), which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Apixaban is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
References Luettgen, J. M., et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T., et al.: J. Thromb. Thrombol., 31, 310 (2011); Barrett, Y. C., et al.: Thromb. Haemos., 105, 181 (2011);

Formula: C₁₁H₁₁ClN₂O

Color and Shape: Neat

Molecular weight: 222.671

Ref: TR-A180180

Apixaban Impurity 87

CAS: 1801881-15-1

Formula: C₁₁H₁₁ClN₂O

Molecular weight: 222.67

Ref: ST-EA-CP-A3104